Toward a better understanding of factor XI activation.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

5 citing papers in PubMed.

1. Fluorescent Activity-Based Probe To Image and Inhibit Factor XIa Activity in Human Plasma.Journal of medicinal chemistry · 2023
   Article
2. Nanobodies against factor XI apple 3 domain inhibit binding of factor IX and reveal a novel binding site for high molecular weight kininogen.Journal of thrombosis and haemostasis : JTH · 2022
   Article
3. Structural insights into the activation of blood coagulation factor XI zymogen by thrombin: A computational molecular dynamics study.Biophysical chemistry · 2022
   Article
4. Role of platelets in regulating activated coagulation factor XI activity.American journal of physiology. Cell physiology · 2021
   Article
5. Protease activity in single-chain prekallikrein.Blood · 2020
   Article

Corrections and comments

• Comment on
  Hydrogen-deuterium exchange mass spectrometry highlights conformational changes induced by factor XI activation and binding of factor IX to factor XIa.2019

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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