ReviewChemistry (Weinheim an der Bergstrasse, Germany)2020
The Mechanism of N-Heterocyclic Carbene Organocatalysis through a Magnifying Glass.
Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Carbon and Heteroatom Activation via N-Heterocyclic Carbene-Bound Dearomative Intermediates for Stereoselective Annulation Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Review
- The Genuine Carbene Conundrum.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Review
- Dynamic Protonation States Underlie Carbene Formation in ThDP-Dependent Enzymes: A Theoretical Study.The journal of physical chemistry. B · 2023Article
- Oxidative N-Heterocyclic Carbene Catalysis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Review
- Formation of Breslow Intermediates from N-Heterocyclic Carbenes and Aldehydes Involves Autocatalysis by the Breslow Intermediate, and a Hemiacetal.Angewandte Chemie (International ed. in English) · 2022Article
- Arenesulfonyl indole: new precursor for diversification of C-3 functionalized indoles.RSC advances · 2021Review
- Preferential N-H⋯:C[double bond splayed right] hydrogen bonding involving ditopicRSC advances · 2020Article
- N-Heterocyclic Carbene Organocatalysis: With or Without Carbenes?Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- The Mechanism of N-Heterocyclic Carbene Organocatalysis through a Magnifying Glass.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The term "N-Heterocyclic carbene organocatalysis" is often invoked in organic synthesis for reactions that are catalyzed by different azolium salts in the presence of bases. Although the mechanism of these reactions is considered today evident, a closer look into the details that have been collected throughout the last century reveals that there are many open questions and even contradictions in the field. Emerging new theoretical and experimental results offer solutions to these problems, because they show that through considering alternative reaction mechanisms a more consistent picture on the catalytic process can be obtained. These novel perspectives will be able to extend the scope of the reactions that we call today N-heterocyclic carbene organocatalysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.