ArticleStatistics in medicine2020
Ecological inference for infectious disease data, with application to vaccination strategies.
Article in Statistics in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Association between pertussis vaccination coverage and other sociodemographic factors and pertussis incidence using surveillance data.Epidemics · 2023Article
- Assessing uncertainty of voter transitions estimated from aggregated data. Application to the 2017 French presidential election.Journal of applied statistics · 2020Article
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Authors and funding
2 authors.
Funding
Abstract
Disease surveillance systems provide a rich source of data regarding infectious diseases, aggregated across geographical regions. The analysis of such ecological data is fraught with difficulties, and, unless care and suitable data summaries are available, will lead to biased estimates of individual-level parameters. We consider using surveillance data to study the impacts of vaccination. To catalog the problems of ecological inference, we start with an individual-level model, which contains familiar parameters, and derive an ecologically consistent model for infectious diseases in partially vaccinated populations. We compare with other popular model classes and highlight deficiencies. We explore the properties of the new model through simulation and demonstrate that, under standard assumptions, the ecological model provides less biased estimates. We then fit the new model to data collected on measles outbreaks in Germany from 2005-2007.
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Registered trials
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