Evidence map›Paper›PMID 31797357›Full record

ReviewThe British journal of surgery2020

Evaluation of appendicitis risk prediction models in adults with suspected appendicitis.

A Bhangu, RIFT Study Group on behalf of the West Midlands Research Collaborative

Registry-linked trialOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The British journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05178251 (Impact of SARS-Cov2 Pandemic on Severity of Perioperative Complications in Patients Undergoing Appendectomy), which is not on this map. Cited by 66 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 8 pooled it
24.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05178251 completednot on this map

Impact of SARS-Cov2 Pandemic on Severity of Perioperative Complications in Patients Undergoing Appendectomy

TypeobservationalSponsorCentral Hospital, Nancy, FranceRan2018 to 2024Enrolled300ConditionsPostoperative Complications, Appendicitis, COVID-19 Pandemic, Appendicitis With PeritonitisArmsappendectomy
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 8 syntheses or guidelines pooled it, 144 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
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  6. Pooled it
  7. Pooled it
  8. Magnetic resonance imaging (MRI) for diagnosis of acute appendicitis.The Cochrane database of systematic reviews · 2021
    Pooled it
  9. Trial
  10. Trial
  11. A Case Report of Acute Appendicitis Complicated by Appendicoliths.Journal of education & teaching in emergency medicine · 2026
    Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Review
  17. Review
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

A Bhangu
RIFT Study Group on behalf of the West Midlands Research Collaborative
University of Birmingham · GB

Funding

Cancer Research UK 24430Cancer Research UK 27981Department of Health NIHR300175Medical Research Council MR/M009157/1Medical Research Council MR/S001751/1
6 · The paper itself

Abstract

backgroundAppendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis.

methodsA systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16-45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis).

resultsSome 5345 patients across 154 UK hospitals were identified, of which two-thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut-off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut-off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent).

conclusionWomen in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision-making by identifying adults in the UK at low risk of appendicitis were identified.

Indexed as

Decision MakingEmergency Service, HospitalAdultAppendectomyAppendicitisHumansRisk Assessment

Identifiers

PMID31797357
PMCPMC6972511
OpenAlexW2997823537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.