Evidence map›Paper›PMID 31797255›Full record

ArticleMolecular and cellular biochemistry2020

Ephx2-gene deletion affects acetylcholine-induced relaxation in angiotensin-II infused mice: role of nitric oxide and CYP-epoxygenases.

Ahmad Hanif, Matthew L Edin, Darryl C Zeldin, Mohammed A Nayeem

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Integrated bioinformatics to identify and validate the role of oxidative stress-related gene EPHX2 in laryngeal cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Adenosine AMolecular and cellular biochemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ahmad HanifPharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV, USA.
Matthew L EdinDivision of Intramural Research, NIEHS/NIH, Research Triangle Park, NC, USA.
Darryl C ZeldinDivision of Intramural Research, NIEHS/NIH, Research Triangle Park, NC, USA.
Mohammed A NayeemPharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV, USA. mnayeem@hsc.wvu.edu.ORCID http://orcid.org/0000-0002-7827-4760
Research Triangle Park Foundation · USWest Virginia University · US

Funding

Characterization And Functional Significance Of P450 Arachidonate EpoxygenasesZIAES025034 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 2009 to 2025
$18.6M
P450 Arachidonate EpoxygenasesZ01ES025034 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 1995 to 2008
$2.2M
Role of Cyp2j-epoxygenases, sEH and PPARs in adenosine-induced vascular responseR01HL114559 · NHLBI · WEST VIRGINIA UNIVERSITY · PI NAYEEM, MOHAMMED A · 2013 to 2017
$1.5M
Intramural NIH HHS Z01 ES025034NHLBI NIH HHS HL-114559NHLBI NIH HHS R01 HL114559NIEHS NIH HHS Z01 ES025034
6 · The paper itself

Abstract

Previously, we showed that adenosine A

Indexed as

Gene DeletionVasodilationAcetylcholineAngiotensin IIAnimalsCytochrome P450 Family 2Epoxide HydrolasesMiceMice, KnockoutNitric OxideAcetylcholineAngiotensin IICyp2c29 protein, mouseCytochrome P450 Family 2Ephx2 protein, mouseEpoxide HydrolasesNitric OxideAcetylcholineAdenosine A2A receptorCYP-epoxgenasesNitric oxideRelaxationSoluble epoxide hydrolase

Identifiers

PMID31797255
PMCPMC6957727
OpenAlexW2991672625

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.