ArticleScientific reports2019
Draft genome of Tanacetum cinerariifolium, the natural source of mosquito coil.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 35 citations in OpenAlex.
- Larvicidal Activity, GC-MS Profiling and Multitarget Molecular Docking of Essential Oils fromMolecules (Basel, Switzerland) · 2026Article
- Genetic diversity and structure of the endemic Tanacetum cinerariifolium as a consequence of multiple processes operating at different temporal scales.Scientific reports · 2025Article
- Asteraceae genome database: a comprehensive platform for Asteraceae genomics.Frontiers in plant science · 2024Article
- Creating Pyrethrin Mimetic Phosphonates as Chemical Genetics Tools Targeting the GDSL Esterase/Lipase TcGLIP to Investigate Pyrethrin Biosynthesis.Journal of medicinal chemistry · 2023Article
- Genome sequencing reveals chromosome fusion and extensive expansion of genes related to secondary metabolism in Artemisia argyi.Plant biotechnology journal · 2022Article
- TcGLIP GDSL Lipase Substrate Specificity Co-determines the Pyrethrin Composition inJournal of agricultural and food chemistry · 2022Article
- Development of Microsatellite Markers forPlants (Basel, Switzerland) · 2022Article
- Draft Genome of Tanacetum Coccineum: Genomic Comparison of Closely Related Tanacetum-Family Plants.International journal of molecular sciences · 2022Article
- Overexpression ofPlants (Basel, Switzerland) · 2022Article
- TcMYC2 regulates Pyrethrin biosynthesis inHorticulture research · 2022Article
- A chromosome-level genome sequence of Chrysanthemum seticuspe, a model species for hexaploid cultivated chrysanthemum.Communications biology · 2021Article
- Research advances in and prospects of ornamental plant genomics.Horticulture research · 2021Review
- How Plants Synthesize Pyrethrins: Safe and Biodegradable Insecticides.Trends in plant science · 2020Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pyrethrum (Tanacetum cinerariifolium), which is a perennial Asteraceae plant with white daisy-like flowers, is the original source of mosquito coils and is known for the biosynthesis of the pyrethrin class of natural insecticides. However, the molecular basis of the production of pyrethrins by T. cinerariifolium has yet to be fully elucidated. Here, we present the 7.1-Gb draft genome of T. cinerariifolium, consisting of 2,016,451 scaffolds and 60,080 genes predicted with high confidence. Notably, analyses of transposable elements (TEs) indicated that TEs occupy 33.84% of the genome sequence. Furthermore, TEs of the sire and oryco clades were found to be enriched in the T. cinerariifolium-specific evolutionary lineage, occupying a total of 13% of the genome sequence, a proportion approximately 8-fold higher than that in other plants. InterProScan analysis demonstrated that biodefense-related toxic proteins (e.g., ribosome inactivating proteins), signal transduction-related proteins (e.g., histidine kinases), and metabolic enzymes (e.g., lipoxygenases, acyl-CoA dehydrogenases/oxygenases, and P450s) are also highly enriched in the T. cinerariifolium genome. Molecular phylogenetic analysis detected a variety of enzymes with genus-specific multiplication, including both common enzymes and others that appear to be specific to pyrethrin biosynthesis. Together, these data identify possible novel components of the pyrethrin biosynthesis pathway and provide new insights into the unique genomic features of T. cinerariifolium.
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