ArticleScience signaling2019
The interaction of ceramide 1-phosphate with group IVA cytosolic phospholipase A
Abstract read
In one paragraph
Article in Science signaling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Oral Recombinant Human Collagen III Protects Gastric Mucosa via G-Quadruplex-Mediated Activation of the Pla2g4a-Prostaglandin Axis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The lncRNA, CyKILRb acts as a ceRNA for tumor suppressive microRNA to augment oncogenic phenotype via induction of PIK3R2/PIMolecular therapy. Nucleic acids · 2026Article
- cPLAScience advances · 2026Article
- Oral Supplementation of n-3 Polyunsaturated Fatty Acids (n-3-PUFA) Can Prevent TBI-Induced Visual, Motor, and Emotional Deficits in Mice.Molecular neurobiology · 2025Article
- RNA splicing variants of the novel long non-coding RNA, CyKILR, possess divergent biological functions in non-small cell lung cancer.Molecular therapy. Nucleic acids · 2025Article
- Sphingolipid changes in mouse brain and plasma after mild traumatic brain injury at the acute phases.Lipids in health and disease · 2024Article
- Sphingolipid biosynthetic inhibitor L-Cycloserine prevents oxidative-stress-mediated death in an in vitro model of photoreceptor-derived 661W cells.Experimental eye research · 2024Article
- Article
- Role of Polyunsaturated Fatty Acids (PUFAs) and Eicosanoids on Dry Eye Symptoms and Signs.Biomolecules · 2024Article
- Differential lipid signaling from CD4Frontiers in immunology · 2024Article
- Fluoxetine restrains allergic inflammation by targeting an FcɛRI-ATP positive feedback loop in mast cells.Science signaling · 2023Article
- Skewing cPLAScience signaling · 2023Article
- Gene expression changes in therapeutic ultrasound-treated venous leg ulcers.Frontiers in medicine · 2023Article
- Ceramide Kinase Inhibition Drives Ferroptosis and Sensitivity to Cisplatin in Mutant KRAS Lung Cancer by Dysregulating VDAC-Mediated Mitochondria Function.Molecular cancer research : MCR · 2022Article
- Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis.Molecular cancer research : MCR · 2022Article
- Dysfunction of ABC Transporters at the Surface of BBB: Potential Implications in Intractable Epilepsy and Applications of Nanotechnology Enabled Drug Delivery.Current drug metabolism · 2022Review
- Evidence for Systemic Reactive Oxygen Species in UVB-mediated Microvesicle Formation.Photochemistry and photobiology · 2022Article
- Systemic Elevation of n-3 Polyunsaturated Fatty Acids (n-3-PUFA) Is Associated with Protection against Visual, Motor, and Emotional Deficits in Mice following Closed-Head Mild Traumatic Brain Injury.Molecular neurobiology · 2021Article
- Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris.JCI insight · 2021Article
- Updating Phospholipase ABiomolecules · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
H Patrick MacKnightDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0003-3232-6155
Daniel J StephensonDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0002-5698-3400
L Alexis HoeferlinDepartment of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0001-7569-8712
Savannah D BenusaDepartment of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia, VA 23298, USA.ORCID 0000-0002-1430-9928
James T DeLigioDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0001-8560-8469
Kenneth D MausDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0002-2868-2934
Anika N AliDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0003-4762-2520
Jennifer S WayneDepartment of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA.
Margaret A ParkDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, FL 33620, USA.
Edward H HinchcliffeHormel Institute, University of Minnesota, Austin, MN 55912, USA.
Rhoderick E BrownHormel Institute, University of Minnesota, Austin, MN 55912, USA.ORCID 0000-0002-7337-3604
John J RyanDepartment of Biology, Virginia Commonwealth University, Richmond, VA 23298, USA.
Robert F DiegelmannDepartment of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA 23298, USA.
Charles E ChalfantDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, FL 33620, USA. cechalfant@usf.edu.
Funding
Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Kim Felder Rhoads · 1985 to 2026
$51.0MNational Metabolomics Data Repository - nextgen Metabolomics WorkbenchU2CDK119886 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUBRAMANIAM, SHANKAR · 2018 to 2021
$12.7MThe utilization of photonics technology to rapidly detect bioactive lipids associated with preeclampsia developmentU01HD087198 · NICHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI CHALFANT, CHARLES E., WALSH, SCOTT W · 2015 to 2015
$4.2MThe functional role of the cPLA2alpha/C1P interaction in sepsis resolutionR01HL125353 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI BROWN, RHODERICK E, CHALFANT, CHARLES E. · 2014 to 2018
$4.0MGGT Targeting Suppresses Mast Cell Activation by IgE and IL-33R01AI138495 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI RYAN, JOHN J · 2018 to 2022
$2.2MSSRIs Inhibit IgE-mediated Mast Cell FunctionR21AI138494 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI RYAN, JOHN J · 2019 to 2020
$403kThe role of the C1P/cPLA2-alpha interaction in eicosanoid biosynthesis.F32AI108088 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI HOEFERLIN, LAUREN ALEXIS · 2014 to 2015
$109kBLRD VA I01 BX001792BLRD VA IK6 BX004603NCI NIH HHS P30 CA016059NHLBI NIH HHS R01 HL125353NIAID NIH HHS F32 AI108088NIAID NIH HHS R01 AI138495NIAID NIH HHS R21 AI138494NICHD NIH HHS U01 HD087198NIDDK NIH HHS U2C DK119886
Abstract
The sphingolipid ceramide 1-phosphate (C1P) directly binds to and activates group IVA cytosolic phospholipase A
Indexed as
Wound HealingAnimalsCell MovementCell NucleusCell ProliferationCeramidesCollagenCytoplasmCytosolDinoprostoneEicosanoidsFibroblastsGenotypeGroup IV Phospholipases A2Hydroxyeicosatetraenoic AcidsInflammation5-hydroxy-6,8,11,14-eicosatetraenoic acidceramide 1-phosphateCeramidesCollagenDinoprostoneEicosanoidsGroup IV Phospholipases A2Hydroxyeicosatetraenoic AcidsPla2g4d protein, mouseThromboxane B2
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.