Evidence map›Paper›PMID 31796566›Full record

ArticlemSystems2019

Regulation of AmpC-Driven β-Lactam Resistance in Pseudomonas aeruginosa: Different Pathways, Different Signaling.

Gabriel Torrens, Sara Belén Hernández, Juan Alfonso Ayala, Bartolome Moya, Carlos Juan, Felipe Cava, Antonio Oliver

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Antibiotic Nanoparticles-Loaded Wound Dressings AgainstInternational journal of nanomedicine · 2024
    Pooled it
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  10. Identification of a novel gene inAntimicrobial agents and chemotherapy · 2026
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  14. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
  15. Article
  16. Multidrug-resistantVirulence · 2025
    Review
  17. Article
  18. A clinically relevant reinterpretation of disk approximation testing for inducible AmpC inRevista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Article
  19. Activity of cefiderocol againstMicrobiology spectrum · 2025
    Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Gabriel Torrens *Servicio de Microbiología and Unidad de Investigación, Hospital Son Espases, Instituto de Investigación Sanitaria de Baleares (IdISBa), Palma, Spain.
Sara Belén Hernández *Laboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå Centre for Microbial Research, Umeå University, Umeå, Sweden.
Juan Alfonso AyalaDepartamento de Virología y Microbiología, Centro de Biología Molecular Severo Ochoa, Madrid, Spain.
Bartolome MoyaServicio de Microbiología and Unidad de Investigación, Hospital Son Espases, Instituto de Investigación Sanitaria de Baleares (IdISBa), Palma, Spain.ORCID https://orcid.org/0000-0001-6404-246X
Carlos JuanServicio de Microbiología and Unidad de Investigación, Hospital Son Espases, Instituto de Investigación Sanitaria de Baleares (IdISBa), Palma, Spain carlos.juan@ssib.es felipe.cava@umu.se.ORCID https://orcid.org/0000-0002-1402-3516
Felipe CavaLaboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå Centre for Microbial Research, Umeå University, Umeå, Sweden carlos.juan@ssib.es felipe.cava@umu.se.
Antonio OliverServicio de Microbiología and Unidad de Investigación, Hospital Son Espases, Instituto de Investigación Sanitaria de Baleares (IdISBa), Palma, Spain.ORCID https://orcid.org/0000-0001-9327-1894
Health Research Institute of the Balearic Islands · ESUmeå University · SECentro de Biología Molecular Severo Ochoa · ESUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hyperproduction of the chromosomal AmpC β-lactamase is the main mechanism driving β-lactam resistance in

Indexed as

AmpC β-lactamasemuropeptidepeptidoglycanPseudomonas aeruginosa

Identifiers

PMID31796566
PMCPMC6890930
OpenAlexW2992674733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.