Evidence map›Paper›PMID 31796523›Full record

ArticleG3 (Bethesda, Md.)2020

Origin and Evolution of Two Independently Duplicated Genes Encoding UDP- Glucose: Glycoprotein Glucosyltransferases in

Diego A Caraballo, Lucila I Buzzi, Carlos P Modenutti, Ana Acosta-Montalvo, Olga A Castro, María S Rossi

Erratum issuedAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. N-glycan-dependent protein maturation and quality control in the ER.Nature reviews. Molecular cell biology · 2025
    Review
  2. Selective involvement of UGGT variant: UGGT2 in protecting mouse embryonic fibroblasts from saturated lipid-induced ER stress.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Diego A CaraballoCONICET-Universidad de Buenos Aires, IFIBYNE, Buenos Aires, Argentina, Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular, Buenos Aires, Argentina, dcaraballo@fbmc.fcen.uba.ar.ORCID 0000-0002-0345-7861
Lucila I BuzziCONICET-Universidad de Buenos Aires, IQUIBICEN, Buenos Aires, Argentina; Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Química Biológica, Buenos Aires, Argentina.
Carlos P ModenuttiCONICET-Universidad de Buenos Aires, IQUIBICEN, Buenos Aires, Argentina; Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Química Biológica, Buenos Aires, Argentina, and.ORCID 0000-0001-5352-7234
Ana Acosta-MontalvoCONICET-Universidad de Buenos Aires, IQUIBICEN, Buenos Aires, Argentina; Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología y Biología Molecular y Celular, Buenos Aires, Argentina.
Olga A CastroCONICET-Universidad de Buenos Aires, IQUIBICEN, Buenos Aires, Argentina; Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología y Biología Molecular y Celular, Buenos Aires, Argentina.ORCID 0000-0001-5984-1080
María S RossiCONICET-Universidad de Buenos Aires, IFIBYNE, Buenos Aires, Argentina, Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular, Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

UDP- glucose: glycoprotein glucosyltransferase (UGGT) is a protein that operates as the gatekeeper for the endoplasmic reticulum (ER) quality control mechanism of glycoprotein folding. It is known that vertebrates and

Indexed as

Evolution, MolecularGene DuplicationAmino Acid SequenceAnimalsBinding SitesCaenorhabditisCatalytic DomainComputational BiologyGanglioside GalactosyltransferaseGlucosyltransferasesModels, MolecularPhylogenyProtein BindingStructure-Activity RelationshipVertebratesGanglioside GalactosyltransferaseGlucosyltransferasesCaenorhabditis elegansNeofunctionalizationPositive selectionPurifying selectionUDP- glucose: glycoprotein glucosyltransferaseVertebrates

Identifiers

PMID31796523
PMCPMC7003075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.