ArticleInfectious diseases of poverty2019
High insecticide resistance in the major malaria vector Anopheles coluzzii in Chad Republic.
Article in Infectious diseases of poverty, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 31 citations in OpenAlex.
- High resistance of Anopheles gambiae s.L. populations to public health insecticides in Ghana: contribution of domestic and agricultural pesticide use.BMC infectious diseases · 2026Article
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- First report of widespread kdr-L995F pyrethroid-resistant An. arabiensis and Temporal trends of pyrethroid resistance in urban Ilorin, Kwara State, Nigeria.BMC infectious diseases · 2025Article
- Characterizing the escalation of pyrethroid resistance and its impact on bed nets efficacy alongside molecular basis in Anopheles funestus from Cameroon.Malaria journal · 2025Article
- First large-scale assessment of pyrethroid resistance in Anopheles darlingi (Diptera: Culicidae) in Brazil (2021-2024): a crucial step in informing decision-making in malaria control.Malaria journal · 2025Article
- Article
- Cost of the national malaria control program and cost-effectiveness of indoor residual spraying and insecticide-treated bed net interventions in two districts of Madagascar.Cost effectiveness and resource allocation : C/E · 2024Article
- Resistance of Anopheles gambiae s.s. against commonly used insecticides and implication of cytochrome P450 monooxygenase in resistance to pyrethroids in Lambaréné (Gabon).BMC infectious diseases · 2024Article
- Exploring the molecular mechanisms of increased intensity of pyrethroid resistance in Central African population of a major malaria vectorEvolutionary applications · 2024Article
- Molecular drivers of insecticide resistance in the Sahelo-Sudanian populations of a major malaria vector Anopheles coluzzii.BMC biology · 2023Article
- Bendiocarb and Malathion Resistance in Two Major Malaria Vector Populations in Cameroon Is Associated with High Frequency of the G119S Mutation (Ace-1) and Overexpression of Detoxification Genes.Pathogens (Basel, Switzerland) · 2022Article
- Molecular Drivers of Multiple and Elevated Resistance to Insecticides in a Population of the Malaria VectorGenes · 2022Article
- Distribution of acetylcholinesterase (Ace-1Parasites & vectors · 2022Article
- Article
- Urban malaria in sub-Saharan Africa: dynamic of the vectorial system and the entomological inoculation rate.Malaria journal · 2021Review
- Review
- Article
- Pyrethroid Resistance Aggravation in Ugandan Malaria Vectors Is Reducing Bednet Efficacy.Pathogens (Basel, Switzerland) · 2021Article
- From Global to Local-New Insights into Features of Pyrethroid Detoxification in Vector Mosquitoes.Insects · 2021Review
- Article
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9 authors at 4 institutions in 4 countries.
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Abstract
backgroundThe Sahel region of Chad Republic is a prime candidate for malaria pre-elimination. To facilitate pre-elimination efforts in this region, two populations of Anopheles coluzzii from Central Chad Republic were characterized, their insecticide resistance profile and the possible molecular mechanisms driving the resistance in the field investigated.
methodsBloodfed female Anopheles gambiae s.l. resting indoor, were collected at N'djamena and Massakory, Chad in 2018 and characterized for species composition, and infection rate was determined using the TaqMan assay. Susceptibility to various insecticides was assessed using WHO tube bioassays. Cone bioassays were conducted using various long-lasting insecticidal nets (LLINs). Results were analysed using Chi Square test. Knockdown resistance (kdr) and ace-1 markers were investigated by TaqMan genotyping.
resultsAnopheles coluzzii was the major vector found in N'djamena (100%) and Massakory (~ 94%). No Plasmodium was found in 147 bloodfed F
conclusionsMultiple resistance in An. coluzzii populations from Chad highlight challenges associated with deployment of LLINs and indoor residual spraying (IRS) in the Sahel of this country. The pyrethroid-synergists LLINs (e.g. PermaNet®3.0) and organophosphate-based IRS maybe the alternatives for malaria control in this region.
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