Evidence map›Paper›PMID 31796037›Full record

ArticleJournal of translational medicine2019

The prognostic role of circulating CD8

Ning An, Haoyi Wang, Wenxiao Jia, Wang Jing, Chao Liu, Hui Zhu, Jinming Yu

Open access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. CD4Trends in cancer · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Elicitation of stem-like CD8Journal for immunotherapy of cancer · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. [Immune Characteristics of Small Cell Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ning AnDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong University, Jinan, China.
Haoyi WangDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Wenxiao JiaDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Wang JingDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Chao LiuDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Hui ZhuDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China. drzhuh@126.com.
Jinming YuDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong University, Jinan, China. sdyujingming@163.com.
Shandong First Medical University · CNShandong Tumor Hospital · CNQilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmunosuppression caused by tumorigenesis may promote tumor progress and invasion. Here, we investigated whether the characteristics of circulating T lymphocyte subtypes in patients with extensive small cell lung cancer (ED-SCLC) can be used as an alternative marker of tumor progression.

methodsThis study included 36 newly diagnosed ED-SCLC patients before treatment and the patients were followed up. 22 age and sex-matched healthy volunteers were selected as control. The percentages and proliferation potential of T lymphocyte subpopulations from peripheral blood were measured.

resultsCD4

conclusionThe present study indicates that SCLC patients have impaired immunity in peripheral blood, and the proliferation potential of circulating CD8

Indexed as

Cell MovementAdultAgedAged, 80 and overAntigens, CDBiomarkers, TumorCase-Control StudiesCD8-Positive T-LymphocytesCell ProliferationDisease-Free SurvivalFemaleHumansKaplan-Meier EstimateLung NeoplasmsLymphocyte SubsetsMaleAntigens, CDBiomarkers, TumorCD8+ T cellsImmunosuppressionPeripheral lymphocytesSmall cell lung cancer

Identifiers

PMID31796037
PMCPMC6892179
OpenAlexW2994091659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.