ArticleBMC public health2019
Age, maturation and serum lipid parameters: findings from the German Health Survey for Children and Adolescents.
Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Total cholesterol and low-density lipoprotein alterations in children and adolescents from Brazil: a prevalence meta-analysis.Archives of endocrinology and metabolism · 2023Pooled it
- Cardiovascular Risk Factor Trajectories and Their Association with Subclinical Atherosclerosis in Children and Adolescents with Congenital Heart Disease: Findings from a 5-Year Follow-up Study.Pediatric cardiology · 2026Article
- Genetic screening of children for familial hypercholesterolaemia: the VRONI study.European heart journal · 2026Article
- Combined Effects of Mediterranean Diet Adherence and Physical Activity on Metabolic Homeostasis and Beta-Cell Function in Male Adolescents.Nutrients · 2026Observational
- Assessment of Machine Learning Model Performance for Clinical Prediction of Insulin Resistance in the Study of Cardiovascular Risk in Adolescents-ERICA.Journal of clinical medicine · 2026Article
- Routine lipid profiles in allergic disease: a mini review.Frontiers in allergy · 2026Review
- Lipid Profile and Management of Dyslipidemias in Pregnancy.Journal of cardiovascular development and disease · 2025Review
- Article
- Multicenter Analysis of Cardiometabolic-Related Diagnoses in Youth With Congenital Adrenal Hyperplasia: A PEDSnet Study.The Journal of clinical endocrinology and metabolism · 2025Article
- Plasma Lipidomics of Preadolescent Children: A Hokkaido Study.Journal of lipids · 2025Article
- Alterations in lipid profiles in children with perinatally acquired HIV infection living in Ghana: A cross-sectional study.PloS one · 2025Article
- Maintaining optimal cardiovascular health metrics and carotid intima-media thickness among Korean adolescents.Clinical hypertension · 2025Article
- Tracking of serum lipids from prepuberty to young adulthood: results from the KiGGS cohort study.Lipids in health and disease · 2024Article
- Associations of per- and polyfluoroalkyl substances and heavy metals with blood lipid profiles in a representative sample of Korean adolescents.Environmental health : a global access science source · 2024Article
- Characteristics, Physiopathology and Management of Dyslipidemias in Pregnancy: A Narrative Review.Nutrients · 2024Review
- Indications of younger age at menarche in Greek adolescents but with no relation to body mass index.Hormones (Athens, Greece) · 2024Article
- Establishing non-fasting reference values for plasma lipids levels based on age, sex, and puberty stage in a French-Canadian pediatric population.Lipids in health and disease · 2024Article
- Attendance-Based Adherence and Outcomes of Obesity Management Program in Arab Adolescents.Children (Basel, Switzerland) · 2023Article
- Tracking of serum lipids in healthy children on a year-to-year basis.BMC cardiovascular disorders · 2023Article
- Abnormal HDL lipid and protein composition following pediatric cancer treatment: an associative study.Lipids in health and disease · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundRecommendations on preventive lipid screening among children and adolescents remain controversial. The aim of the study was to assess age and puberty-related changes in serum lipids, including total cholesterol (TC), and high-density (HDL-C) and non-high-density lipoprotein cholesterol (Non-HDL-C).
methodsUsing cross-sectional data from the National Health Interview and Examination Survey for Children and Adolescents in Germany (KiGGS 2003-2006; N = 13,676; 1-17 years), changes in distributions of serum lipids were visualized according to sex, age and maturation. Youth aged 10-17 years were classified as prepubescent, early/mid-puberty, and mature/advanced puberty. Multiple linear regressions were used to quantify the impact of pubertal stage on serum lipid levels, adjusted for potential confounding factors.
resultsAmong children 1-9 years mean serum lipid measures increased with age, with higher mean TC and Non-HDL-C among girls than boys. Among children 10-17 years, advanced pubertal stage was independently related to lower lipid measures. Adjusted mean TC, HDL-C and Non-HDL-C was 19.4, 5.9 and 13.6 mg/dL lower among mature/advanced puberty compared to prepubescent boys and 11.0, 4.0 and 7.0 mg/dL lower in mature/advanced puberty compared to prepubescent girls.
conclusionsLipid concentrations undergo considerable and sex-specific changes during physical growth and sexual maturation and significantly differ between pubertal stages. Screening recommendations need to consider the fluctuations of serum lipids during growth and sexual maturation.
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