ArticleBMC genomics2019
Weighted gene co-expression network analysis unveils gene networks associated with the Fusarium head blight resistance in tetraploid wheat.
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- Transcriptomic insights into the biocontrol mechanism of Trichoderma spp. against Fusarium wilt in melon.Stress biology · 2026Article
- Comparative transcriptomes reveal insights into different host responses associated with Fusarium head blight resistance in wheat.BMC plant biology · 2025Article
- Identification of miRNAs associated with Aspergillus flavus infection and their targets in groundnut (Arachis hypogaea L.).BMC plant biology · 2025Article
- Dissecting adult plant resistance to stem rust through multi-model GWAS in a diverse barley germplasm panel.Frontiers in plant science · 2025Article
- Transcriptome profiling of eight Zea mays lines identifies genes responsible for the resistance to Fusarium verticillioides.BMC plant biology · 2024Article
- Identification of candidate genes for Fusarium head blight resistance from QTLs using RIL population in wheat.Plant molecular biology · 2024Article
- Broad-spectrum resistance to fungal foliar diseases in wheat: recent efforts and achievements.Frontiers in plant science · 2024Review
- Recent advances in exploring transcriptional regulatory landscape of crops.Frontiers in plant science · 2024Review
- Article
- Identification of fusarium head blight resistance markers in a genome-wide association study of CIMMYT spring synthetic hexaploid derived wheat lines.BMC plant biology · 2023Article
- A Survey of the Transcriptomic Resources in Durum Wheat: Stress Responses, Data Integration and Exploitation.Plants (Basel, Switzerland) · 2023Review
- Multi-locus genome-wide association studies reveal the genetic architecture ofFrontiers in plant science · 2023Article
- Biocontrol potential and action mechanism ofFrontiers in microbiology · 2023Article
- Unraveling Plant-Pathogen Interactions in Cereals Using RNA-seq.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Development and Molecular Cytogenetic Identification of Two Wheat-International journal of molecular sciences · 2022Article
- Transcriptome Analysis ofGenes · 2022Article
- Gene regulatory networks for compatible versus incompatible grafts identify a role for SlWOX4 during junction formation.The Plant cell · 2022Article
- Article
- Fusarium head blight resistance in European winter wheat: insights from genome-wide transcriptome analysis.BMC genomics · 2021Article
- Gene co-expression network analysis reveals key pathways and hub genes in Chinese cabbage (Brassica rapa L.) during vernalization.BMC genomics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFusarium head blight (FHB) resistance in the durum wheat breeding gene pool is rarely reported. Triticum turgidum ssp. carthlicum line Blackbird is a tetraploid relative of durum wheat that offers partial FHB resistance. Resistance QTL were identified for the durum wheat cv. Strongfield × Blackbird population on chromosomes 1A, 2A, 2B, 3A, 6A, 6B and 7B in a previous study. The objective of this study was to identify the defense mechanisms underlying the resistance of Blackbird and report candidate regulator defense genes and single nucleotide polymorphism (SNP) markers within these genes for high-resolution mapping of resistance QTL reported for the durum wheat cv. Strongfield/Blackbird population.
resultsGene network analysis identified five networks significantly (P < 0.05) associated with the resistance to FHB spread (Type II FHB resistance) one of which showed significant correlation with both plant height and relative maturity traits. Two gene networks showed subtle differences between Fusarium graminearum-inoculated and mock-inoculated plants, supporting their involvement in constitutive defense. The candidate regulator genes have been implicated in various layers of plant defense including pathogen recognition (mainly Nucleotide-binding Leucine-rich Repeat proteins), signaling pathways including the abscisic acid and mitogen activated protein (MAP) kinase, and downstream defense genes activation including transcription factors (mostly with dual roles in defense and development), and cell death regulator and cell wall reinforcement genes. The expression of five candidate genes measured by quantitative real-time PCR was correlated with that of RNA-seq, corroborating the technical and analytical accuracy of RNA-sequencing.
conclusionsGene network analysis allowed identification of candidate regulator genes and genes associated with constitutive resistance, those that will not be detected using traditional differential expression analysis. This study also shed light on the association of developmental traits with FHB resistance and partially explained the co-localization of FHB resistance with plant height and maturity QTL reported in several previous studies. It also allowed the identification of candidate hub genes within the interval of three previously reported FHB resistance QTL for the Strongfield/Blackbird population and associated SNPs for future high resolution mapping studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.