Evidence map›Paper›PMID 31795916›Full record

ArticleOpen biology2019

Identification of four unconventional kinetoplastid kinetochore proteins KKT22-25 in

Olga O Nerusheva, Patryk Ludzia, Bungo Akiyoshi

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
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  5. Immunoprecipitation of Protein Complexes from Trypanosoma brucei.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  6. CRISPR-Cas9 precision editing of kinetochore protein phosphosite codons inFrontiers in cellular and infection microbiology · 2026
    Article
  7. Article
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  9. Biomolecular NMR assignments · 2025
    Article
  10. Article
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  15. Article
  16. Lessons from the deep: mechanisms behind diversification of eukaryotic protein complexes.Biological reviews of the Cambridge Philosophical Society · 2023
    Article
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Olga O NerushevaDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Patryk LudziaDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Bungo AkiyoshiDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
University of Oxford · GB

Funding

Wellcome Trust 210622/Z/18/Z
6 · The paper itself

Abstract

The kinetochore is a multi-protein complex that drives chromosome segregation in eukaryotes. It assembles onto centromere DNA and interacts with spindle microtubules during mitosis and meiosis. Although most eukaryotes have canonical kinetochore proteins, kinetochores of evolutionarily divergent kinetoplastid species consist of at least 20 unconventional kinetochore proteins (KKT1-20). In addition, 12 proteins (KKT-interacting proteins 1-12, KKIP1-12) are known to localize at kinetochore regions during mitosis. It remains unclear whether KKIP proteins interact with KKT proteins. Here, we report the identification of four additional kinetochore proteins, KKT22-25, in

Indexed as

ImmunoprecipitationKinetochoresProtozoan ProteinsTrypanosoma brucei bruceiProtozoan ProteinscentromereGcn5-related N-acetyltransferasekinetochorekinetoplastidTrypanosoma brucei

Identifiers

PMID31795916
PMCPMC6936259
OpenAlexW2988707325

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.