ArticleJournal of the International Association of Providers of AIDS Care
Psychosocial Well-Being and HIV-Related Immune Health Outcomes among HIV-Positive Older Adults: Support for a Biopsychosocial Model of HIV Stigma and Health.
Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Health Outcomes Associated with Loneliness and Social Isolation in Older Adults Living with HIV: A Systematic Review.AIDS and behavior · 2025Pooled it
- HIV/AIDS stigma and psychological well-being after 40 years of HIV/AIDS: a systematic review and meta-analysis.European journal of psychotraumatology · 2021Pooled it
- Pharmacological and Nonpharmacological Interventions to Address Insomnia Symptoms and Poor Sleep Quality Among People With HIV: Protocol for a Scoping Review.JMIR research protocols · 2026Article
- The burden of HIV-related stigma on clinical and quality of life outcomes: results from a systematic literature review.Health psychology and behavioral medicine · 2026Review
- COVID-19 pandemic-related stress and substance use behaviors among people with HIV - a mixed method analysis.PloS one · 2026Article
- Inside out: TNFa-RII and sexualized drug use in acute HIV predicts persistent depressive symptoms despite antiretroviral therapy.Brain, behavior, & immunity - health · 2025Article
- Discrimination and Mental Health Among Black and Latino People Living with HIV: Understanding the Role of Religion and Spirituality.AIDS and behavior · 2025Article
- Knowledge and stigma of people living with HIV treated in a medication dispensing unit: a cross-sectional study.BMC public health · 2025Article
- Exploring Stigma and Self-Image: Mixed-Methods Insights from HIV Cure-Related Research Participants Undergoing Analytical Treatment Interruptions.AIDS patient care and STDs · 2025Observational
- Disrupting the Path from Depression to Loneliness: Multilevel Resilience among Older Sexual Minority Men with and without HIV.AIDS and behavior · 2024Article
- United Voices Group-Singing Intervention to Address Loneliness and Social Isolation Among Older People With HIV During the COVID-19 Pandemic: Intervention Adaption Study.JMIR formative research · 2024Article
- Empowering people living with HIV (PLHIV): unveiling care gaps and identifying opportunities for improving care for PLHIV in Singapore and Hong Kong.Journal of the International AIDS Society · 2024Article
- Exploring the Impact of Experiences with Everyday and Major Discrimination and HIV-Related Stigma on Engagement in HIV Care Among Older African Americans Living with HIV.Journal of racial and ethnic health disparities · 2023Article
- Preventing Neurocognitive Decline in Adults Aging with HIV: Implications for Practice and Research.Journal of Alzheimer's disease : JAD · 2023Review
- Article
- The employment situation of people living with HIV: a closer look at the effects of the 2008 economic crisis.The European journal of health economics : HEPAC : health economics in prevention and care · 2022Article
- Applying the biopsychosocial model to unpack a psychosocial support intervention designed to improve antiretroviral treatment outcomes for adolescents in South Africa.The Pan African medical journal · 2022Article
- Loneliness, Risky Beliefs and Intentions about Practicing Safer Sex among Methamphetamine Dependent Individuals.Substance use & misuse · 2022Article
- Loneliness: An Immunometabolic Syndrome.International journal of environmental research and public health · 2021Review
- A Photovoice Exploration of the Lived Experience of Intersectional Stigma among People Living with HIV.Archives of sexual behavior · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Evidence suggests that psychosocial stress negatively impacts immunological health in HIV-positive individuals. However, few studies have explored this association in substance-using older adults living with HIV (OALWH). We evaluated the effect of depression, loneliness, substance use problems, and HIV stigma on primary markers of immune function in a sample of 120 OALWH with substance-related issues. HIV stigma correlated with the greatest number of factors, including depression, loneliness, and substance use problems. Older age and antiretroviral adherence were associated with viral suppression, which was in turn associated with higher percentage of CD4 count. Multivariate path analyses demonstrated that lower HIV stigma and viral suppression were the only factors independently associated with higher percentage of CD4 count, with a significant indirect effect of adherence on CD4 through viral suppression. HIV stigma emerged as the most salient factor associated with both psychosocial well-being and immune health in the current study, suggesting that it is a critical factor to consider in future interventions for the rapidly growing population of OALWH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.