SynthesisAmerican journal of men's health
Relationship Between Cannabis Use and Erectile Dysfunction: A Systematic Review and Meta-Analysis.
Synthesis in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- The genetics of cannabis lifetime use.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Pooled it
- Multi-ancestry investigation of the genomics of erectile dysfunction.Nature communications · 2025Pooled it
- Social environmental impact of COVID-19 and erectile dysfunction: an explorative review.Journal of endocrinological investigation · 2022Pooled it
- Penile Hemodynamic Patterns Highlighting the Impact of Diabetes in Young Men With Erectile Dysfunction.Andrology · 2026Article
- Sexual dysfunction and distress in patients with depressive disorders at a tertiary care hospital in Riyadh, Saudi Arabia: a cross-sectional study.BMC psychiatry · 2026Article
- Association between marijuana use and erectile dysfunction in a sample of sexual minority men: a cross-sectional analysis.Journal of cannabis research · 2026Article
- Recreational Cannabis Use During Human Pregnancy: Its Effects on the Placenta and Endocannabinoid System.International journal of molecular sciences · 2026Review
- Molecular Mechanisms of the Endocannabinoid System with a Focus on Reproductive Physiology and the Cannabinoid Impact on Fertility.International journal of molecular sciences · 2025Review
- Reproductive and sexual health concerns in gastrointestinal illness: a narrative review.Translational gastroenterology and hepatology · 2025Review
- Substance Abuse and Sexual Functioning: An Overview of Mechanisms.Addiction & health · 2024Review
- Influence of substance use on male reproductive health and offspring outcomes.Nature reviews. Urology · 2024Review
- Update on cannabis in human sexuality.Psychopharmacology · 2024Review
- Factors Associated with Erectile Dysfunction Among Older Gay Men.Archives of sexual behavior · 2024Article
- Sexual Satisfaction among Lebanese Adults: Scale Validation in Arabic and Correlates Following Two Cross-Sectional Studies.Healthcare (Basel, Switzerland) · 2023Article
- Understanding the Mechanisms of Action and Effects of Drugs of Abuse.Molecules (Basel, Switzerland) · 2023Review
- The Italian Society of Andrology and Sexual Medicine (SIAMS), along with ten other Italian Scientific Societies, guidelines on the diagnosis and management of erectile dysfunction.Journal of endocrinological investigation · 2023Article
- A comparative study of sexual behavior, dysfunction, satisfaction, relationship, and sexual quality of life amongst treatment-naïve and abstinent men (buprenorphine-maintained) with Opioid (heroin) dependence syndrome.Indian journal of psychiatry · 2023Article
- Medicinal Plants Used in the Management of Sexual Dysfunction, Infertility and Improving Virility in the East African Community: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2023Review
- Impact of cannabinoids on pregnancy, reproductive health, and offspring outcomes.American journal of obstetrics and gynecology · 2022Review
- Current state of cannabis use, policies, and research across sixteen countries: cross-country comparisons and international perspectives.Trends in psychiatry and psychotherapy · 2022Article
Corrections and comments
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Authors and funding
9 authors at 8 institutions in 3 countries.
Funding
Abstract
Globally, there is increasing usage and legalization of cannabis. In addition to its reported therapeutic effects, cannabis has several health risks which are not clearly defined. Erectile dysfunction (ED) is the most common male sexual disorder and there are plausible mechanisms linking cannabis use to ED. No attempt has been made to collate the literature on this topic. The aim of this review was to summarize the prevalence and risk of ED in cannabis users compared to controls. A systematic review of major databases from inception to January 1, 2019, without language restriction, was undertaken to identify studies investigating cannabis use and presence of ED. The analysis compared the prevalence of ED in cannabis users versus controls. Consequently, the odds ratio (OR) with 95% confidence intervals (CI) was calculated, applying a random-effect model. Five case-control studies were included with data from 3,395 healthy men, 1,035 using cannabis (smoking) and 2,360 nonusers. The overall prevalence of ED in cannabis users was 69.1% (95% CI: 38.0-89.1), whilst the correspondent figure in controls was 34.7% (95% CI: 20.3-52.7). The OR of ED in cannabis users was almost four times that of controls (OR = 3.83; 95% CI: 1.30-11.28;
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.