Evidence map›Paper›PMID 31795766›Full record

ArticleEuropean journal of preventive cardiology2020

Influence of visceral adiposity accumulation on adverse left and right ventricular mechanics in the community.

Naoko Sawada, Koki Nakanishi, Masao Daimon, Yuriko Yoshida, Jumpei Ishiwata, Megumi Hirokawa, Tomoko Nakao, Hiroyuki Morita, Marco R Di Tullio, Shunichi Homma and 1 more

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Article in European journal of preventive cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Aging and myocardial strain.Journal of medical ultrasonics (2001) · 2022
    Review
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  17. Regional adiposity, cardiorespiratory fitness, and left ventricular strain: an analysis from the Dallas Heart Study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Naoko SawadaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Koki NakanishiDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Masao DaimonDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Yuriko YoshidaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Jumpei IshiwataDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Megumi HirokawaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Tomoko NakaoDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Hiroyuki MoritaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Marco R Di TullioDepartment of Medicine, Columbia University, New York, NY, USA.
Shunichi HommaDepartment of Medicine, Columbia University, New York, NY, USA.
Issei KomuroDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsObesity carries significant risk for unfavorable ventricular remodeling and subsequent heart failure (HF) development, although the association between abdominal fat distribution and subclinical ventricular dysfunction is unclear. This study aimed to compare the subcutaneous and visceral abdominal adiposity with the risk of decreased ventricular strain.

methodsWe included 340 participants without overt cardiac disease who underwent laboratory testing, abdominal computed tomographic examination, and speckle-tracking echocardiography. Abdominal adiposity was quantitatively assessed as visceral fat area (VFA) and subcutaneous fat area (SFA) at the level of the umbilicus. Speckle-tracking echocardiography was performed to assess left ventricular global longitudinal strain (LVGLS) and right ventricular free-wall longitudinal strain (RVLS).

resultsMean age was 56 ± 9 years, and 244 of the participants (72%) were male. The mean LVGLS and RVLS were -19.1 ± 3.0% and -25.0 ± 4.1%, respectively. Both VFA and SFA correlated with LVGLS (

conclusionIn a sample of the general population, VFA, but not SFA, accumulation was significantly associated with decreased LV and RV strain, an association that may be involved in the increased risk of HF in obese individuals.

Indexed as

AdiposityAbdominal FatEchocardiographyFemaleFollow-Up StudiesHeart FailureHeart VentriclesHumansIncidenceJapanMaleMiddle AgedObesity, AbdominalRetrospective StudiesRisk AssessmentRisk FactorsEchocardiographylongitudinal strainsubcutaneous fatvisceral fat

Identifiers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.