Evidence map›Paper›PMID 31795726›Full record

ArticleASN neuro

Neuronal Conditional Knockout of Collapsin Response Mediator Protein 2 Ameliorates Disease Severity in a Mouse Model of Multiple Sclerosis.

Aubin Moutal, Sergey Kalinin, Kathy Kowal, Natalia Marangoni, Jeffrey Dupree, Shao Xia Lin, Kinga Lis, Lucia Lisi, Kenneth Hensley, Rajesh Khanna and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ASN neuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. TheFrontiers in physiology · 2023
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aubin MoutalUniversity of Arizona, Tucson, AZ, USA.
Sergey KalininUniversity of Illinois, Chicago, IL, USA.
Kathy KowalUniversity of Illinois, Chicago, IL, USA.
Natalia MarangoniUniversity of Illinois, Chicago, IL, USA.
Jeffrey DupreeVirginia Commonwealth University, Richmond, VA, USA.
Shao Xia LinUniversity of Illinois, Chicago, IL, USA.
Kinga LisUniversity of Illinois, Chicago, IL, USA.
Lucia LisiUniversita Cattolica del Sacro Cuore, Rome, Italy.
Kenneth HensleyArkansas College of Osteopathic Medicine, Fort Smith, AR, USA.
Rajesh KhannaUniversity of Arizona, Tucson, AZ, USA.ORCID 0000-0002-9066-2969
Douglas L FeinsteinUniversity of Illinois, Chicago, IL, USA.ORCID 0000-0003-2815-2885

Funding

CRMP2, mitochondria, and Huntington’s diseaseR01NS098772 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI BRUSTOVETSKY, NICKOLAY, KHANNA, RAJESH · 2017 to 2021
$2.8M
CRMP2, Nav1.7 sodium channel, and chronic painR01DA042852 · NIDA · UNIVERSITY OF ARIZONA · PI KHANNA, RAJESH · 2017 to 2021
$1.9M
BLRD VA IK6 BX004852NIDA NIH HHS R01 DA042852NINDS NIH HHS R01 NS098772
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBrainDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalIntercellular Signaling Peptides and ProteinsMiceMice, KnockoutMultiple SclerosisNerve Tissue ProteinsNeuronsSpinal Cordcollapsin response mediator protein-2Intercellular Signaling Peptides and ProteinsNerve Tissue ProteinsCRMP2EAELKEmultiple sclerosisspinal cordupper motor neurons

Identifiers

PMID31795726
PMCPMC6893573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.