ReviewThe Journal of the Acoustical Society of America2019
The rat animal model for noise-induced hearing loss.
Review in The Journal of the Acoustical Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Octave band noise exposure: Laboratory models and otoprotection efforts.The Journal of the Acoustical Society of America · 2019Pooled it
- From Anatomy to Application: A Comprehensive Review of Nanovesicular Systems for Otic Drug Delivery.AAPS PharmSciTech · 2026Review
- Prolonged intermittent theta burst stimulation enhances hippocampal plasticity via GluN2A-mediated signaling.Frontiers in aging neuroscience · 2026Article
- Resveratrol Mitigates Noise-Induced Cochlear Damage and Delays Hearing Loss in Wistar Rats.BioMed research international · 2026Article
- Calpain2-mediated downregulation of apoptosis-inducing factors impairs mitochondrial function in noise-induced spiral ganglion neuron degeneration.IBRO neuroscience reports · 2025Article
- Developmental timing of auditory deprivation influences spatial memory and hippocampal plasticity in rats.Scientific reports · 2025Article
- Study Models for Non-Syndromic Hearing Loss.Cells · 2025Review
- Noise-Induced Hearing Loss: Overview and Future Prospects for Research on Oxidative Stress.International journal of molecular sciences · 2025Review
- Distortion-product Otoacoustic Emissions in Diagnostic Versus Portable Equipment: A Comparison of Animal Models.International archives of otorhinolaryngology · 2025Article
- Article
- Gating-spring stiffness increases outer-hair-cell bundle stiffness, damping, and receptor current.Scientific reports · 2024Article
- Acoustic noise in a small-format 3.0-T neonatal MRI system.Pediatric radiology · 2024Article
- Sheep as a large animal model for hearing research: comparison to common laboratory animals and humans.Laboratory animal research · 2023Review
- Article
- Redox Imbalance as a Common Pathogenic Factor Linking Hearing Loss and Cognitive Decline.Antioxidants (Basel, Switzerland) · 2023Review
- Chronic stress from adolescence to adulthood increases adiposity and anxiety in rats with decreased expression ofFrontiers in genetics · 2023Article
- Underlying neural mechanisms of degraded speech intelligibility following noise-induced hearing loss: The importance of distorted tonotopy.Hearing research · 2022Review
- Characteristics of gut microbiota in representative mice strains: Implications for biological research.Animal models and experimental medicine · 2022Article
- Article
- The impact of targeted ablation of one row of outer hair cells and Deiters' cells on cochlear amplification.Journal of neurophysiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rats make excellent models for the study of medical, biological, genetic, and behavioral phenomena given their adaptability, robustness, survivability, and intelligence. The rat's general anatomy and physiology of the auditory system is similar to that observed in humans, and this has led to their use for investigating the effect of noise overexposure on the mammalian auditory system. The current paper provides a review of the rat model for studying noise-induced hearing loss and highlights advancements that have been made using the rat, particularly as these pertain to noise dose and the hazardous effects of different experimental noise types. In addition to the traditional loss of auditory function following acoustic trauma, recent findings have indicated the rat as a useful model in observing alterations in neuronal processing within the central nervous system following noise injury. Furthermore, the rat provides a second animal model when investigating noise-induced cochlear synaptopathy, as studies examining this in the rat model resemble the general patterns observed in mice. Together, these findings demonstrate the relevance of this animal model for furthering the authors' understanding of the effects of noise on structural, anatomical, physiological, and perceptual aspects of hearing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.