ReviewThe Journal of the Acoustical Society of America2019
The use of nonhuman primates in studies of noise injury and treatment.
Review in The Journal of the Acoustical Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Transduction Efficiency and Immunogenicity of Viral Vectors for Cochlear Gene Therapy: A Systematic Review of Preclinical Animal Studies.Frontiers in cellular neuroscience · 2021Pooled it
- Cochlear histopathology in macaques after noise-induced temporary threshold shifts.Hearing research · 2026Article
- Persistent impairment of spatial hearing and neural binaural interaction after "temporary" noise-induced hearing loss.bioRxiv : the preprint server for biology · 2026Article
- Treating Hearing Loss: From Cochlear Implantation to Gene Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Contribution of displacement, duration, and velocity on auditory motion direction perception in macaque monkeys.Scientific reports · 2025Article
- Noise-Induced Hearing Loss: Overview and Future Prospects for Research on Oxidative Stress.International journal of molecular sciences · 2025Review
- Contributions and future potential of animal models for geroscience research on sensory systems.GeroScience · 2025Review
- Hierarchical differences in the encoding of amplitude modulation in the subcortical auditory system of awake nonhuman primates.Journal of neurophysiology · 2024Article
- Towards the Clinical Application of Gene Therapy for Genetic Inner Ear Diseases.Journal of clinical medicine · 2023Review
- Deep intracochlear injection of triamcinolone-acetonide with an inner ear catheter in patients with residual hearing.Frontiers in neuroscience · 2023Article
- Investigation of inner ear drug delivery with a cochlear catheter in piglets as a representative model for human cochlear pharmacokinetics.Frontiers in pharmacology · 2023Article
- Audiologic characterization using clinical physiological measures: Normative data from macaque monkeys.Hearing research · 2022Article
- An assessment of ambient noise and other environmental variables in a nonhuman primate housing facility.Lab animal · 2022Article
- Three psychophysical metrics of auditory temporal integration in macaques.The Journal of the Acoustical Society of America · 2021Article
- Correlations between cochlear pathophysiology and behavioral measures of temporal and spatial processing in noise exposed macaques.Hearing research · 2021Article
- Changes in audiometric threshold and frequency selectivity correlate with cochlear histopathology in macaque monkeys with permanent noise-induced hearing loss.Hearing research · 2020Article
- Noise-Induced Hearing Loss and its Prevention: Current Issues in Mammalian Hearing.Current opinion in physiology · 2020Article
- Noise-induced hearing loss: Translating risk from animal models to real-world environments.The Journal of the Acoustical Society of America · 2019Review
- Noise-induced hearing loss and its prevention: Integration of data from animal models and human clinical trials.The Journal of the Acoustical Society of America · 2019Review
- Use of the guinea pig in studies on the development and prevention of acquired sensorineural hearing loss, with an emphasis on noise.The Journal of the Acoustical Society of America · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Exposure to prolonged or high intensity noise increases the risk for permanent hearing impairment. Over several decades, researchers characterized the nature of harmful noise exposures and worked to establish guidelines for effective protection. Recent laboratory studies, primarily conducted in rodent models, indicate that the auditory system may be more vulnerable to noise-induced hearing loss (NIHL) than previously thought, driving renewed inquiries into the harmful effects of noise in humans. To bridge the translational gaps between rodents and humans, nonhuman primates (NHPs) may serve as key animal models. The phylogenetic proximity of NHPs to humans underlies tremendous similarity in many features of the auditory system (genomic, anatomical, physiological, behavioral), all of which are important considerations in the assessment and treatment of NIHL. This review summarizes the literature pertaining to NHPs as models of hearing and noise-induced hearing loss, discusses factors relevant to the translation of diagnostics and therapeutics from animals to humans, and concludes with some of the practical considerations involved in conducting NHP research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.