ReviewMaterials (Basel, Switzerland)2019
Bioactive Glass-Based Endodontic Sealer as a Promising Root Canal Filling Material without Semisolid Core Materials.
Review in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Comparison of sealer penetration of sonic activation versus conventional needle irrigation: a systematic review and meta-analysis of randomized controlled trials.BMC oral health · 2022Pooled it
- Bridging the Break: Three Approaches to Root Fracture Management Using Bioactive Glass Material, Fiber Post, and Orthodontic Stabilization: A Case Series.Iranian endodontic journal · 2026Article
- Functional and Bioactive Performance of Premixed Bioceramic Sealers with Warm Obturation: A Scoping Review.Gels (Basel, Switzerland) · 2025Review
- In Vitro Bioactivity and Cytotoxicity Assessment of Two Root Canal Sealers.Materials (Basel, Switzerland) · 2025Article
- Effect of low-level laser therapy on postoperative pain following root canal filling with resin-based and bioceramic sealers: A double-blinded randomized clinical trial.Journal of conservative dentistry and endodontics · 2025Article
- Chemical and Biological Properties of C-Point Obturation Cones.Biomimetics (Basel, Switzerland) · 2025Article
- Evaluating the penetration, interfacial adaptation, and push-out bond strength of four bioceramic-based root canal sealers.BMC oral health · 2025Article
- Article
- Calcium Silicate-Based Sealers: Apatite Deposition on Root Canal Dentin and pH Variation Analysis.European journal of dentistry · 2025Article
- Bioceramics in Endodontics: Limitations and Future Innovations-A Review.Dentistry journal · 2025Review
- Article
- Root canal therapy combined with endoscopic sinus surgery for odontogenic sinusitis: Efficacy comparison in a cohort study.World journal of clinical cases · 2025Article
- Clinical outcome of root canal obturation using different based sealers: a retrospective cohort study.BMC oral health · 2024Article
- An In Vitro Comparative Analysis of Physico-Mechanical Properties of Commercial and Experimental Bioactive Endodontic Sealers.Bioengineering (Basel, Switzerland) · 2024Article
- The effect of bioactive glass-based, bioceramic based and epoxy amine resin based root canal sealers on post-obturation pain: A double blinded randomized controlled trial.Journal of conservative dentistry and endodontics · 2024Article
- Antibacterial Efficacy of Mineral Trioxide Aggregate, Bioactive Glass and Epoxy-Resin Based Sealer: AnJournal of pharmacy & bioallied sciences · 2024Article
- Physicochemical properties of AH plus bioceramic sealer, Bio-C Sealer, and ADseal root canal sealer.Head & face medicine · 2024Article
- Interfacial adaptation of newly prepared nano-tricalcium silicate-58s bioactive glass-based endodontic sealer.Journal of dental research, dental clinics, dental prospects · 2024Article
- Biological properties versus solubility of endodontic sealers and cements.Biomaterial investigations in dentistry · 2024Review
- Sol-Gel Technologies to Obtain Advanced Bioceramics for Dental Therapeutics.Molecules (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endodontic treatment for a tooth with damaged dental pulp aims to both prevent and cure apical periodontitis. If the tooth is re-infected as a result of a poorly obturated root canal, periapical periodontitis may set-in due to invading bacteria. To both avoid any re-infection and improve the success rate of endodontic retreatment, a treated root canal should be three-dimensionally obturated with a biocompatible filling material. Recently, bioactive glass, one of the bioceramics, is focused on the research area of biocompatible biomaterials for endodontics. Root canal sealers derived from bioactive glass-based have been developed and applied in clinical endodontic treatments. However, at present, there is little evidence about the patient outcomes, sealing mechanism, sealing ability, and removability of the sealers. Herein, we have developed a bioactive glass-based root canal sealer and provided evidence concerning its physicochemical properties, biocompatibility, sealing ability, and removability. We also review the classification of bioceramics and characteristics of bioactive glass. Additionally, we describe the application of bioactive glass to facilitate the development of a new root canal sealer. Furthermore, this review shows the potential application of bioactive glass-based cement as a root canal filling material in the absence of semisolid core material.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.