Evidence map›Paper›PMID 31795429›Full record

ArticleMolecules (Basel, Switzerland)2019

Anti-Inflammatory Derivatives with Dual Mechanism of Action from the Metabolomic Screening of

Olívia da S Domingos, Bianca G V Alcântara, Mário F C Santos, Tatiane C S Maiolini, Danielle F Dias, João L Baldim, João Henrique G Lago, Marisi G Soares, Daniela A Chagas-Paula

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Susceptibility ofMolecules (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Natural Products Drug Discovery: On Silica or In-Silico?Handbook of experimental pharmacology · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Olívia da S DomingosInstituto de Química-Universidade Federal de Alfenas, Alfenas 37130-001, MG, Brazil.ORCID 0000-0003-3371-5777
Bianca G V AlcântaraInstituto de Química-Universidade Federal de Alfenas, Alfenas 37130-001, MG, Brazil.
Mário F C SantosInstituto de Química-Universidade Federal de Alfenas, Alfenas 37130-001, MG, Brazil.
Tatiane C S MaioliniInstituto de Química-Universidade Federal de Alfenas, Alfenas 37130-001, MG, Brazil.
Danielle F DiasInstituto de Química-Universidade Federal de Alfenas, Alfenas 37130-001, MG, Brazil.
João L BaldimInstituto de Química-Universidade Federal de Alfenas, Alfenas 37130-001, MG, Brazil.
João Henrique G LagoCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo Andre 09606-045, SP, Brazil.ORCID 0000-0002-1193-8374
Marisi G SoaresInstituto de Química-Universidade Federal de Alfenas, Alfenas 37130-001, MG, Brazil.
Daniela A Chagas-PaulaInstituto de Química-Universidade Federal de Alfenas, Alfenas 37130-001, MG, Brazil.

Funding

FAPEMIG APQ-02353-17
6 · The paper itself

Abstract

Metabolomics approaches have become fundamental strategies for the analysis of complex mixtures, guiding the isolation of target compounds by focusing on unpublished or promising pharmacological properties. The discovery of novel anti-inflammatory agents is important due to several limitations regarding their potency, efficacy, and adverse effects. Thus, novel anti-inflammatory candidates are essential, aiming to find agents with better mechanisms of action. In this context, extracts from

Indexed as

MetabolomicsAnimalsAnti-Inflammatory AgentsEdemaFabaceaeMaleMiceNeutrophil InfiltrationNeutrophilsPlant ExtractsAnti-Inflammatory AgentsPlant Extractsanti-inflammatoryflavonoidsmetabolomicsPoincianella pluviosa

Identifiers

PMID31795429
PMCPMC6930619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.