ReviewMolecules (Basel, Switzerland)2019
Inhibitors of Brassinosteroid Biosynthesis and Signal Transduction.
Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Hormone-metabolism crosstalk in plants: an integrated signaling network coordinating growth and stress adaptation.Plant signaling & behavior · 2026Review
- Brassinosteroid Synthesis and Perception Differently Regulate Phytohormone Networks inInternational journal of molecular sciences · 2025Article
- Crucial Roles of Brassinosteroids in Cell Wall Composition and Structure Across Species: New Insights and Biotechnological Applications.Plant, cell & environment · 2025Review
- Squalene acts as a feedback signaling molecule in facilitating bidirectional communication between tea plants.Science advances · 2025Article
- Genetic dissection of ten photosynthesis-related traits based on InDel- and SNP-GWAS in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Genome-wide methylation, transcriptome and characteristic metabolites reveal the balance between diosgenin and brassinosteroids inHorticulture research · 2024Article
- Brassinosteroid Signaling Pathways: Insights into Plant Responses under Abiotic Stress.International journal of molecular sciences · 2023Review
- Biosynthetic Pathways of Hormones in Plants.Metabolites · 2023Review
- Insights on Phytohormonal Crosstalk in Plant Response to Nitrogen Stress: A Focus on Plant Root Growth and Development.International journal of molecular sciences · 2023Review
- Brassinosteroids (BRs) Role in Plant Development and Coping with Different Stresses.International journal of molecular sciences · 2022Review
- SlCESTA Is a Brassinosteroid-Regulated bHLH Transcription Factor of Tomato That Promotes Chilling Tolerance and Fruit Growth When Over-Expressed.Frontiers in plant science · 2022Article
- 24-epibrassinolide confers tolerance against deep-seeding stress inPlant signaling & behavior · 2021Article
- BIN2 negatively regulates plant defence against Verticillium dahliae in Arabidopsis and cotton.Plant biotechnology journal · 2021Article
- Effects of brassinolide on the growing of rice plants.Journal of pesticide science · 2021Article
- Brassinolide Enhances the Level of Brassinosteroids, Protein, Pigments, and Monosaccharides inPlants (Basel, Switzerland) · 2021Article
- Brassinosteroid Signaling, Crosstalk and, Physiological Functions in Plants Under Heavy Metal Stress.Frontiers in plant science · 2021Review
- The BAHD Acyltransferase BIA1 Uses Acetyl-CoA for Catabolic Inactivation of Brassinosteroids.Plant physiology · 2020Article
- Gaining Insight into Exclusive and Common Transcriptomic Features Linked to Drought and Salinity Responses across Fruit Tree Crops.Plants (Basel, Switzerland) · 2020Article
- Comprehensive Overview of the Brassinosteroid Biosynthesis Pathways: Substrates, Products, Inhibitors, and Connections.Frontiers in plant science · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemical inhibitors are invaluable tools for investigating protein function in reverse genetic approaches. Their application bears many advantages over mutant generation and characterization. Inhibitors can overcome functional redundancy, their application is not limited to species for which tools of molecular genetics are available and they can be applied to specific tissues or developmental stages, making them highly convenient for addressing biological questions. The use of inhibitors has helped to elucidate hormone biosynthesis and signaling pathways and here we review compounds that were developed for the plant hormones brassinosteroids (BRs). BRs are steroids that have strong growth-promoting capacities, are crucial for all stages of plant development and participate in adaptive growth processes and stress response reactions. In the last two decades, impressive progress has been made in BR inhibitor development and application, which has been instrumental for studying BR modes of activity and identifying and characterizing key players. Both, inhibitors that target biosynthesis, such as brassinazole, and inhibitors that target signaling, such as bikinin, exist and in a comprehensive overview we summarize knowledge and methodology that enabled their design and key findings of their use. In addition, the potential of BR inhibitors for commercial application in plant production is discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.