ReviewJournal of fungi (Basel, Switzerland)2019
Molecular Diagnostics of Mucormycosis in Hematological Patients: A Literature Review.
Review in Journal of fungi (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Molecular diagnosis of rhino-orbital mucormycosis in a COVID-19 setting.International ophthalmology · 2023Article
- Recent Developments in the Diagnosis of Mucormycosis.Journal of fungi (Basel, Switzerland) · 2022Review
- Prevalence of COVID-19 Associated Mucormycosis in a German Tertiary Care Hospital.Journal of fungi (Basel, Switzerland) · 2022Article
- Mucormycosis: An opportunistic pathogen during COVID-19.Environmental research · 2021Review
- An Overview of the Management of the Most Important Invasive Fungal Infections in Patients with Blood Malignancies.Infection and drug resistance · 2020Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesto analyze the results of molecular methods applying for the diagnosis of mucormycosis in hematologic patients based on a literature review. DATA SOURCES: A systematic search in databases PubMed, Google Scholar for August 2019. Review eligibility criteria: original articles published in English, studies of molecular methods for the diagnosis of mucormycosis in hematologic patients.
resultsWe analyzed the research data from 116 hematological patients with mucormycosis, including children (6%). Patients with localized forms of mucormycosis prevailed (72%), and lung involvement was diagnosed in 58% of these cases. For molecular verification of the causative agent of mucormycosis, blood serum was most often used, less commonly postoperative and autopsy material, biopsy specimens, formalin-fixed paraffin-embedded samples and bronchoalveolar lavage, pleural fluid and sputum. The sensitivity of molecular diagnostics of mucormycosis in a cohort of hematological patients was 88.2%.
conclusionThe use of molecular techniques along with standard mycological methods will improve the diagnostics of mucormycosis in hematologic patients. However, prospective studies of the effectiveness of molecular methods for the diagnosis of mucormycosis of various etiologies in hematological patients, including children, using bronchoalveolar lavage (BAL) and cerebrospinal fluid (CSF) are needed.
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Registered trials
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