Evidence map›Paper›PMID 31795313›Full record

ArticleCancers2019

Association of Polyps with Early-Onset Colorectal Cancer and Throughout Surveillance: Novel Clinical and Molecular Implications.

José Perea García, Julia Arribas, Ángel Cañete, Juan Luis García, Edurne Álvaro, Sandra Tapial, Cristina Narváez, Alfredo Vivas, Lorena Brandáriz, Sergio Hernández-Villafranca and 9 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  6. Article
  7. Identification of driving genes of familial adenomatous polyposis by differential gene expression analysis and weighted gene co-expression network analysis.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 3 countries.

José Perea GarcíaSurgery Department, Fundación Jiménez Díaz University Hospital, 28040 Madrid, Spain.ORCID 0000-0001-5522-8844
Julia ArribasGastroenterology Department, 12 de Octubre University Hospital, 28041 Madrid, Spain.
Ángel CañeteGastroenterology Department, 12 de Octubre University Hospital, 28041 Madrid, Spain.
Juan Luis GarcíaMolecular Medicine Unit Department of Medicine, Biomedical Research Institute of Salamanca (IBSAL) and Institute of Molecular and Cellular Biology of Cancer (IBMCC), University of Salamanca-SACYL-CSIC, 37001 Salamanca, Spain.ORCID 0000-0002-2146-5726
Edurne ÁlvaroSurgery Department, "Infanta Leonor" University Hospital, 28031 Madrid, Spain.ORCID 0000-0001-6793-3188
Sandra TapialDigestive Cancer Research Group, 12 de Octubre Research Institute, 28041 Madrid, Spain.
Cristina NarváezSurgery Department, 12 de Octubre University Hospital, 28041 Madrid, Spain.
Alfredo VivasSurgery Department, 12 de Octubre University Hospital, 28041 Madrid, Spain.
Lorena BrandárizSurgery Department, Fundación Jiménez Díaz University Hospital, 28040 Madrid, Spain.
Sergio Hernández-VillafrancaSurgery Department, Fundación Jiménez Díaz University Hospital, 28040 Madrid, Spain.ORCID 0000-0002-3345-1436
Daniel RuedaDigestive Cancer Research Group, 12 de Octubre Research Institute, 28041 Madrid, Spain.ORCID 0000-0002-5377-8890
Yolanda RodríguezPathology Department, 12 de Octubre University Hospital, 28041 Madrid, Spain.
Jessica Pérez-GarcíaMolecular Medicine Unit Department of Medicine, Biomedical Research Institute of Salamanca (IBSAL) and Institute of Molecular and Cellular Biology of Cancer (IBMCC), University of Salamanca-SACYL-CSIC, 37001 Salamanca, Spain.
Susana Olmedillas-LópezFundación Jiménez Díaz University Hospital Health Research Institute, 28040 Madrid, Spain.ORCID 0000-0002-6535-5852
Damián García-OlmoSurgery Department, Fundación Jiménez Díaz University Hospital, 28040 Madrid, Spain.ORCID 0000-0002-9369-2338
Giulia Martina CavestroGastroenterology and Gastrointestinal Endoscopy Unit, Division of Experimental Oncology, Vita-Salute San Raffaele University, IRCCS Ospedale San Raffaele Scientific Institute, 20132 Milan, Italy.
Miguel UriosteHuman Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain.
Ajay GoelBeckman Research Institute at City of Hope Comprehensive Cancer Center, 1218 S. Fifth Avenue, Monrovia, CA 91016, USA.
Rogelio González-SarmientoMolecular Medicine Unit Department of Medicine, Biomedical Research Institute of Salamanca (IBSAL) and Institute of Molecular and Cellular Biology of Cancer (IBMCC), University of Salamanca-SACYL-CSIC, 37001 Salamanca, Spain.ORCID 0000-0002-2726-6795
Universidad de Salamanca · ESResearch Institute Hospital 12 de Octubre · ESVita-Salute San Raffaele University · ITCity of Hope · USInstituto de Salud Carlos III · ES

Funding

The Biology and Diagnosis of HNPCCR01CA072851 · NCI · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI GOEL, AJAY · 1996 to 2019
$6.6M
Ministerio de Ciencia y Tecnología PI10/00683 and PI16/01650 to J.P, PI16/01920 to R.G.S, PI14/00459NCI NIH HHS number R01 CA72851, CA18172, CA184792, and U01 CA187956 to A.G
6 · The paper itself

Abstract

Early-onset colorectal cancer (EOCRC) is an increasing and worrisome entity. The aim of this study was to analyze its association with polyps concerning prognosis and surveillance. EOCRC cases were compared regarding the presence or absence of associated polyps (clinical and molecular features), during a minimum of 7 years of follow-up. Of 119 cases, 56 (47%) did not develop polyps (NP group), while 63 (53%) did (P group). The NP group showed a predominant location of the CRC in the rectum (50%), of sporadic cases (54%), and diagnosis at advanced stages: Only

Indexed as

early-onset colorectal cancerfollow-uppolyp developmentprognosis

Identifiers

PMID31795313
PMCPMC6966640
OpenAlexW2991145205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.