Evidence map›Paper›PMID 31795306›Full record

ArticleSensors (Basel, Switzerland)2019

Detection of Marker miRNAs, Associated with Prostate Cancer, in Plasma Using SOI-NW Biosensor in Direct and Inversion Modes.

Yuri Ivanov, Tatyana Pleshakova, Kristina Malsagova, Leonid Kurbatov, Vladimir Popov, Alexander Glukhov, Alexander Smirnov, Dmitry Enikeev, Natalia Potoldykova, Boris Alekseev and 5 more

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Yuri IvanovInstitute of Biomedical Chemistry (IBMC), Moscow 119121, Russia.ORCID 0000-0001-5041-1914
Tatyana PleshakovaInstitute of Biomedical Chemistry (IBMC), Moscow 119121, Russia.
Kristina MalsagovaInstitute of Biomedical Chemistry (IBMC), Moscow 119121, Russia.
Leonid KurbatovInstitute of Biomedical Chemistry (IBMC), Moscow 119121, Russia.
Vladimir PopovRzhanov Institute of Semiconductor Physics, Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0000-0002-7415-1405
Alexander GlukhovJoint-Stock Company "Novosibirsk Plant of Semiconductor Devices & DC", Novosibirsk 630082, Russia.
Alexander SmirnovRussian Union of Industrialists and Entrepreneurs, Moscow 109240, Russia.
Dmitry EnikeevInstitute for Urology and Reproductive Health, Sechenov University, Moscow 119992, Russia.
Natalia PotoldykovaInstitute for Urology and Reproductive Health, Sechenov University, Moscow 119992, Russia.
Boris AlekseevFederal State Budgetary Institution National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Moscow 125284, Russia.
Daniyar DolotkazinFederal State Budgetary Institution National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Moscow 125284, Russia.
Andrey KaprinFederal State Budgetary Institution National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Moscow 125284, Russia.
Vadim ZiborovJoint Institute for High Temperatures of Russian Academy of Sciences, Moscow 125412, Russia.ORCID 0000-0001-7942-3337
Oleg PetrovJoint Institute for High Temperatures of Russian Academy of Sciences, Moscow 125412, Russia.
Alexander ArchakovInstitute of Biomedical Chemistry (IBMC), Moscow 119121, Russia.
Institute of Biomedical Chemistry · RUMinistry of Health of the Russian Federation · RUJoint Institute for High Temperatures · RUSechenov University · RUResearch Institute of Semiconductor Devices · RURussian Academy of Entrepreneurship · RURussian Academy of Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Information about the characteristics of measuring chips according to their storage conditions is of great importance for clinical diagnosis. In our present work, we have studied the capability of chips to detect nanowire biosensors when they are either freshly prepared or have been stored for either one or two years in a clean room. Potential to detect DNA oligonucleotides (oDNAs)-synthetic analogues of microRNAs (miRNAs) 198 and 429 that are associated with the development of prostate cancer (PCa)-in buffer solution was demonstrated using a nanowire biosensor based on silicon-on-insulator structures (SOI-NW biosensor). To provide biospecific detection, nanowire surfaces were sensitized with oligonucleotide probes (oDNA probes) complimentary to the known sequences of miRNA 183 and 484. In this study it is demonstrated that freshly prepared SOI-NW biosensor chips with n-type conductance and immobilized oDNA probes exhibit responses to the addition of complimentary oDNAs in buffer, leading to decreases in chips' conductance at a concentration of 3.3 × 10

Indexed as

Biomarkers, TumorBiosensing TechniquesHumansMaleMicroRNAsNanowiresNucleic AcidsProstatic NeoplasmsSiliconBiomarkers, TumorMicroRNAsNucleic AcidsSiliconmiRNAnanowire biosensorprostate cancersilicon-on-insulator

Identifiers

PMID31795306
PMCPMC6928824
OpenAlexW2991423674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.