Evidence map›Paper›PMID 31795283›Full record

ArticleMolecules (Basel, Switzerland)2019

A Comprehensive QSAR Study on Antileishmanial and Antitrypanosomal Cinnamate Ester Analogues.

Freddy A Bernal, Thomas J Schmidt

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Alkyl and Aryl Derivatives Based onMolecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Freddy A BernalInstitut für Pharmazeutische Biologie und Phytochemie (IPBP), Westfälische Wilhelms Universität-Münster, PharmaCampus-Corrensstraße 48, D-48149 Münster, Germany.ORCID 0000-0002-4099-6178
Thomas J SchmidtInstitut für Pharmazeutische Biologie und Phytochemie (IPBP), Westfälische Wilhelms Universität-Münster, PharmaCampus-Corrensstraße 48, D-48149 Münster, Germany.ORCID 0000-0003-2634-9705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parasitic infections like leishmaniasis and trypanosomiasis remain as a worldwide concern to public health. Improvement of the currently available drug discovery pipelines for those diseases is therefore mandatory. We have recently reported on the antileishmanial and antitrypanosomal activity of a set of cinnamate esters where we identified several compounds with interesting activity against

Indexed as

Quantitative Structure-Activity RelationshipAntiprotozoal AgentsCinnamatesEstersLeishmaniaModels, MolecularMolecular StructureParasitic Sensitivity TestsReproducibility of ResultsTrypanosomaAntiprotozoal AgentsCinnamatesEsterscinnamate ester analogueshuman african trypanosomasisleishmaniasisMLROPLS.QSARvalidation

Identifiers

PMID31795283
PMCPMC6930487

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.