Evidence map›Paper›PMID 31795253›Full record

ArticlePharmaceutics2019

Metal-Phenolic Network-Coated Hyaluronic Acid Nanoparticles for pH-Responsive Drug Delivery.

Jung Min Shin, Gwan Hyun Choi, Seok Ho Song, Hyewon Ko, Eun Sook Lee, Jae Ah Lee, Pil J Yoo, Jae Hyung Park

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jung Min ShinSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Gwan Hyun ChoiSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Seok Ho SongSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Hyewon KoSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Eun Sook LeeDepartment of Health Science and Technology, SAIHST, Sungkyunkwan University, Suwon 16419, Korea.
Jae Ah LeeSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Pil J YooSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Jae Hyung ParkSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Sungkyunkwan University · KR

Funding

National Research Foundation of Korea 20100027955National Research Foundation of Korea 2018R1A2B3006080National Research Foundation of Korea 2018R1D1A1B07046908
6 · The paper itself

Abstract

Although self-assembled nanoparticles (SNPs) have been used extensively for targeted drug delivery, their clinical applications have been limited since most of the drugs are released into the blood before they reach their target site. In this study, metal-phenolic network (MPN)-coated SNPs (MPN-SNPs), which consist of an amphiphilic hyaluronic acid derivative, were prepared to be a pH-responsive nanocarrier to facilitate drug release in tumor microenvironments (TME). Due to their amphiphilic nature, SNPs were capable of encapsulating doxorubicin (DOX), chosen as the model anticancer drug. Tannic acid and FeCl

Indexed as

drug deliveryhyaluronic acidmetal-phenolic networkpH-responsive particle

Identifiers

PMID31795253
PMCPMC6956368
OpenAlexW2989725231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.