Evidence map›Paper›PMID 31795195›Full record

ArticleCancers2019

Identification of Circulating Genomic and Metabolic Biomarkers in Intrahepatic Cholangiocarcinoma.

Helen Winter, Pamela J Kaisaki, Joe Harvey, Edoardo Giacopuzzi, Matteo P Ferla, Melissa M Pentony, Samantha J L Knight, Ricky A Sharma, Jenny C Taylor, James S O McCullagh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

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  4. Decoding the mechanism for cytotoxicity in thiolato-bridged triosmium carbonyl clusters: from serum reactivity to cellular impact.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Helen WinterNational Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
Pamela J KaisakiNational Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.ORCID 0000-0003-0779-0706
Joe HarveyBristol Cancer Institute, Horfield Rd, Bristol BS2 8ED, UK.ORCID 0000-0001-9047-5672
Edoardo GiacopuzziNational Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.ORCID 0000-0002-5692-366X
Matteo P FerlaNational Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
Melissa M PentonyNational Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.ORCID 0000-0001-6829-6678
Samantha J L KnightNational Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
Ricky A SharmaChemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK.
Jenny C TaylorNational Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.ORCID 0000-0003-3602-5704
James S O McCullaghBristol Cancer Institute, Horfield Rd, Bristol BS2 8ED, UK.
Centre for Human Genetics · GBUniversity of Oxford · GB

Funding

Biotechnology and Biological Sciences Research Council BB/R013829/1Cancer Research UK CRUK/07/030Medical Research Council G0900747Medical Research Council G0900747 91070Wellcome TrustWellcome Trust 090532/Z/09/ZWellcome Trust 204483/Z/16/ZWellcome Trust WT 100127 / R6-338
6 · The paper itself

Abstract

Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer arising from the bile ducts with a need for earlier diagnosis and a greater range of treatment options.

Indexed as

2-hydroxyglutarateCADcirculating DNADHODHIDH1Intrahepatic cholangiocarcinomametabolomicsorotic acidTYMSUMPS

Identifiers

PMID31795195
PMCPMC6966597
OpenAlexW2989579565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.