Evidence map›Paper›PMID 31795172›Full record

ArticleMarine drugs2019

K092A and K092B, Two Peptides Isolated from the Dogfish (

Adrien Bosseboeuf, Amandine Baron, Elise Duval, Aude Gautier, Pascal Sourdaine, Pierrick Auvray

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Adrien BosseboeufNormandy University, University of Caen Normandy (UNICAEN), Sorbonne University, French National Museum of Natural History (MNHN), University of Antilles (UA), French National Centre for Scientific Research (CNRS), French National Institute for Sustainable Development (IRD), Biology of Aquatic Organisms and Ecosystems (BOREA) Research Unit, Sciences Department, CS14032, 14032 CAEN CEDEX 5, France.
Amandine BaronGroup CELLIS PHARMA, Parc Technopolitain Atalante Saint Malo, 35400 Saint Malo, France.
Elise DuvalGroup CELLIS PHARMA, Parc Technopolitain Atalante Saint Malo, 35400 Saint Malo, France.
Aude GautierNormandy University, University of Caen Normandy (UNICAEN), Sorbonne University, French National Museum of Natural History (MNHN), University of Antilles (UA), French National Centre for Scientific Research (CNRS), French National Institute for Sustainable Development (IRD), Biology of Aquatic Organisms and Ecosystems (BOREA) Research Unit, Sciences Department, CS14032, 14032 CAEN CEDEX 5, France.
Pascal SourdaineNormandy University, University of Caen Normandy (UNICAEN), Sorbonne University, French National Museum of Natural History (MNHN), University of Antilles (UA), French National Centre for Scientific Research (CNRS), French National Institute for Sustainable Development (IRD), Biology of Aquatic Organisms and Ecosystems (BOREA) Research Unit, Sciences Department, CS14032, 14032 CAEN CEDEX 5, France.
Pierrick AuvrayGroup CELLIS PHARMA, Parc Technopolitain Atalante Saint Malo, 35400 Saint Malo, France.
Centre Hospitalier de Saint-Malo · FRInstitut de Recherche pour le Développement · FRMuséum national d'Histoire naturelle · FRSorbonne Université · FR

Funding

Conseil Régional de Basse-Normandie and Fonds Européen de Développement Régional 925RD153 and 2890/33528
6 · The paper itself

Abstract

Cancer therapy is currently a major challenge within the research community, especially in reducing the side effects of treatments and to develop new specific strategies against cancers that still have a poor prognosis. In this context, alternative strategies using biotechnologies, such as marine peptides, have been developed based on their promise of effectivity associated with a low toxicity for healthy cells. The purpose of the present paper is to investigate the active mechanism of two peptides that were isolated from the epigonal tissue of the lesser spotted dogfish

Indexed as

DogfishAction PotentialsAnimalsAntineoplastic AgentsAutophagyBreast NeoplasmsCell Line, TumorCell SurvivalMaleMitochondriaPeptidesProstatic NeoplasmsAntineoplastic AgentsPeptidesantineoplasticcancerlesser spotted dogfish (Scyliorhinus canicula)marine peptideMDA-Pca-2bZR-75-1

Identifiers

PMID31795172
PMCPMC6950282
OpenAlexW2991502902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.