Evidence map›Paper›PMID 31795131›Full record

ArticleMolecules (Basel, Switzerland)2019

Sustainable and Selective Extraction of Lipids and Bioactive Compounds from Microalgae.

Ilaria Santoro, Monica Nardi, Cinzia Benincasa, Paola Costanzo, Girolamo Giordano, Antonio Procopio, Giovanni Sindona

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 34 citations in OpenAlex.

  1. Identifying Antimicrobial Agents fromBiotech (Basel (Switzerland)) · 2025
    Article
  2. Enhancing Biomass and Lipid Production inLife (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. A review on prospective production of biofuel from microalgae.Biotechnology reports (Amsterdam, Netherlands) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ilaria SantoroDipartimento di Ingegneria per l'Ambiente e il Territorio e Ingegneria Chimica, Università della Calabria, Cubo 45A, I-87036 Rende, Italy.
Monica NardiDipartimento di Scienze della Salute, Università Magna Græcia, Viale Europa, I-88100 Germaneto (CZ), Italy.ORCID 0000-0001-6617-9320
Cinzia BenincasaCREA Research Centre for Olive, Citrus and Tree Fruit, C.da Li Rocchi, I-87036 Rende, Italy.ORCID 0000-0002-2590-2866
Paola CostanzoDipartimento di Scienze della Salute, Università Magna Græcia, Viale Europa, I-88100 Germaneto (CZ), Italy.ORCID 0000-0002-2205-1541
Girolamo GiordanoDipartimento di Ingegneria per l'Ambiente e il Territorio e Ingegneria Chimica, Università della Calabria, Cubo 45A, I-87036 Rende, Italy.
Antonio ProcopioDipartimento di Scienze della Salute, Università Magna Græcia, Viale Europa, I-88100 Germaneto (CZ), Italy.
Giovanni SindonaDipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, Cubo 12C, I-87036 Rende, Italy.
Magna Graecia University · ITUniversity of Calabria · ITResearch Centre for Olive Growing and Olive Oil Industry · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The procedures for the extraction and separation of lipids and nutraceutics from microalgae using classic solvents have been frequently used over the years. However, these production methods usually require expensive and toxic solvents. Based on our studies involving the use of eco-sustainable methodologies and alternative solvents, we selected ethanol (EtOH) and cyclopentyl methyl ether (CPME) for extracting bio-oil and lipids from algae. Different percentages of EtOH in CPME favor the production of an oil rich in saturated fatty acids (SFA), useful to biofuel production or rich in bioactive compounds. The proposed method for obtaining an extract rich in saturated or unsaturated fatty acids from dry algal biomass is disclosed as eco-friendly and allows a good extraction yield. The method is compared both in extracted oil percentage yield and in extracted fatty acids selectivity to extraction by supercritical carbon dioxide (SC-CO

Indexed as

Biological ProductsChemical FractionationGas Chromatography-Mass SpectrometryLipidsMicroalgaeBiological ProductsLipidsalgal oilbio compoundbiofuelextractiongreen chemistrygreen solvents

Identifiers

PMID31795131
PMCPMC6930523
OpenAlexW2985844149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.