ArticleInternational journal of molecular sciences2019
Genetic and Functional Diversity of Nitrilases in Agaricomycotina.
Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Isolation and Characterization of a Nitrilase-Producing Geotrichum Strain and Optimization of the Fermentation Conditions.Current microbiology · 2025Article
- Metabolism of Aldoximes and Nitriles in Plant-Associated Bacteria and Its Potential in Plant-Bacteria Interactions.Microorganisms · 2022Review
- Phylogenetic and Structural Analysis of Bacterial Nitrilases for the Biodegradation of Nitrile Compounds.Current protein & peptide science · 2022Article
- Phe-140 Determines the Catalytic Efficiency of Arylacetonitrilase fromInternational journal of molecular sciences · 2020Article
- Plant Nitrilase Homologues in Fungi: Phylogenetic and Functional Analysis with Focus on Nitrilases inMolecules (Basel, Switzerland) · 2020Article
- Biocatalysis: "A Jack of all Trades..."International journal of molecular sciences · 2020Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Nitrilases participate in the nitrile metabolism in microbes and plants. They are widely used to produce carboxylic acids from nitriles. Nitrilases were described in bacteria, Ascomycota and plants. However, they remain unexplored in Basidiomycota. Yet more than 200 putative nitrilases are found in this division via GenBank. The majority of them occur in the subdivision Agaricomycotina. In this work, we analyzed their sequences and classified them into phylogenetic clades. Members of clade 1 (61 proteins) and 2 (25 proteins) are similar to plant nitrilases and nitrilases from Ascomycota, respectively, with sequence identities of around 50%. The searches also identified five putative cyanide hydratases (CynHs). Representatives of clade 1 and 2 (NitTv1 from
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Registered trials
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