Evidence map›Paper›PMID 31795092›Full record

ArticleNutrients2019

Anti-Atherosclerotic Properties of Wild Rice in Low-Density Lipoprotein Receptor Knockout Mice: The Gut Microbiome, Cytokines, and Metabolomics Study.

Mohammed H Moghadasian, Ramandeep Kaur, Kayla Kostal, Akhila A Joshi, Mahboubeh Molaei, Khuong Le, Gabor Fischer, Francesca Bonomini, Gaia Favero, Rita Rezzani and 5 more

Abstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mohammed H MoghadasianDepartment of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Ramandeep KaurDepartment of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Kayla KostalDepartment of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Akhila A JoshiDepartment of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Mahboubeh MolaeiCanadian Center for Agri-food Research in Health and Medicine, St. Boniface Hospital Research Center, Winnipeg, MB R2H 2A6, Canada.
Khuong LeCanadian Center for Agri-food Research in Health and Medicine, St. Boniface Hospital Research Center, Winnipeg, MB R2H 2A6, Canada.
Gabor FischerDepartment of Pathology, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Francesca BonominiDepartment of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0001-7210-0308
Gaia FaveroDepartment of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0001-6895-7106
Rita RezzaniDepartment of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0002-7515-5846
Branden S J GregorchukDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Vanessa Leung-ShingDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Michelle WuzinskiDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Andy I SeoDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Denice C BayDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.ORCID 0000-0002-3620-828X

Funding

Natural Sciences and Engineering Research Council of Canada 298450
6 · The paper itself

Abstract

BACKGROUND AND

aimWe previously reported the anti-atherogenic properties of wild rice in low-density lipoprotein receptor knockout (LDL-r-KO) mice. The present study aimed to discover the mechanism of action for such effects. MATERIALS: Fecal and plasma samples from the wild rice treated and control mice were used. Fecal bacterial population was estimated while using 16S rDNA technology. The plasma samples were used to estimate the levels of 35 inflammatory markers and metabolomics, while using Meso Scale multiplex assay and liquid chromatography-mass spectrometry (LC-MS/MS) techniques.

resultsMany bacteria, particularly

conclusionAdditional studies warrant further investigation of the interplay among gut microbiome, inflammatory status, and macronutrient metabolism.

Indexed as

PoaceaeAnimal FeedAnimalsBiomarkersCytokinesDietFecesGastrointestinal MicrobiomeGene Expression RegulationMaleMetabolomicsMiceMice, KnockoutReceptors, LDLBiomarkersCytokinesReceptors, LDL16S rDNAatherosclerosiscarbohydratescytokinesfecesfunctional foodLDL-r-KO micemetabolomicsmicrobiomeplasmaproteinswild rice

Identifiers

PMID31795092
PMCPMC6950250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.