Evidence map›Paper›PMID 31795090›Full record

ArticleMolecules (Basel, Switzerland)2019

Tuning Mechanical Properties of Pseudopeptide Supramolecular Hydrogels by Graphene Doping.

Demetra Giuri, Marianna Barbalinardo, Nicola Zanna, Paolo Paci, Marco Montalti, Massimiliano Cavallini, Francesco Valle, Matteo Calvaresi, Claudia Tomasini

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Phenylalanine-Based Amphiphilic Self-Assembled Materials: Gels or Crystals?Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  2. Review
  3. Article
  4. Controlled Lactonization ofGels (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Controlled Hydrolysis of Odorants Schiff Bases in Low-Molecular-Weight Gels.International journal of molecular sciences · 2022
    Article
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Demetra GiuriDipartimento di Chimica "Giacomo Ciamician", Università di Bologna, Via Selmi, 240126 Bologna, Italy.ORCID 0000-0001-5923-7836
Marianna BarbalinardoIstituto per lo Studio dei Materiali Nanostrutturati, Consiglio Nazionale delle Ricerche, (ISMN-CNR), Via P. Gobetti 101, 40129 Bologna, Italy.
Nicola ZannaDipartimento di Chimica "Giacomo Ciamician", Università di Bologna, Via Selmi, 240126 Bologna, Italy.ORCID 0000-0001-9115-618X
Paolo PaciDipartimento di Chimica "Giacomo Ciamician", Università di Bologna, Via Selmi, 240126 Bologna, Italy.
Marco MontaltiDipartimento di Chimica "Giacomo Ciamician", Università di Bologna, Via Selmi, 240126 Bologna, Italy.ORCID 0000-0001-6227-0899
Massimiliano CavalliniIstituto per lo Studio dei Materiali Nanostrutturati, Consiglio Nazionale delle Ricerche, (ISMN-CNR), Via P. Gobetti 101, 40129 Bologna, Italy.
Francesco ValleIstituto per lo Studio dei Materiali Nanostrutturati, Consiglio Nazionale delle Ricerche, (ISMN-CNR), Via P. Gobetti 101, 40129 Bologna, Italy.ORCID 0000-0001-5793-7206
Matteo CalvaresiDipartimento di Chimica "Giacomo Ciamician", Università di Bologna, Via Selmi, 240126 Bologna, Italy.ORCID 0000-0002-9583-2146
Claudia TomasiniDipartimento di Chimica "Giacomo Ciamician", Università di Bologna, Via Selmi, 240126 Bologna, Italy.ORCID 0000-0002-6310-2704

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2015 project 20157WW5EH
6 · The paper itself

Abstract

Supramolecular hydrogels, obtained from small organic molecules, may be advantageous over polymeric ones for several applications, because these materials have some peculiar properties that differentiate them from the traditional polymeric hydrogels, such as elasticity, thixotropy, self-healing propensity, and biocompatibility. We report here the preparation of strong supramolecular pseudopeptide-based hydrogels that owe their strength to the introduction of graphene in the gelling mixture. These materials proved to be strong, stable, thermoreversible and elastic. The concentration of the gelator, the degree of graphene doping, and the nature of the trigger are crucial to get hydrogels with the desired properties, where a high storage modulus coexists with a good thixotropic behavior. Finally, NIH-3T3 cells were used to evaluate the cell response to the presence of the most promising hydrogels. The hydrogels biocompatibility remains good, if a small degree of graphene doping is introduced.

Indexed as

Mechanical PhenomenaAnimalsBiocompatible MaterialsChemical PhenomenaGraphiteHydrogelsHydrogen-Ion ConcentrationMiceMolecular StructureNIH 3T3 CellsPeptidesPhosphatidylethanolaminesRheologySpectroscopy, Fourier Transform InfraredBiocompatible Materialsdioleoyl phosphatidylethanolamineGraphiteHydrogelsPeptidesPhosphatidylethanolaminesgraphenehydrogelsrheologyself-healingthixotropy

Identifiers

PMID31795090
PMCPMC6930602

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.