ArticleNeuroImage. Clinical2019
Microstructural abnormalities in deep and superficial white matter in youths with mild traumatic brain injury.
Article in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- A systematic review of brain structural and functional alterations in pediatric mild traumatic brain injury.Frontiers in neuroscience · 2026Pooled it
- Characteristic patterns of white matter tract injury in sport-related concussion: An image based meta-analysis.NeuroImage. Clinical · 2020Pooled it
- The second decade of DTI in TBI part 1: a systematic review of mild TBI.Frontiers in neurologyPooled it
- Longitudinal evaluation of white matter tracts post traumatic brain injury using a pediatric porcine model.Journal of neuroscience methods · 2026Article
- U-fiber diffusion kurtosis and susceptibility characteristics in relapsing-remitting multiple sclerosis may be related to cognitive deficits and neurodegeneration.European radiology · 2024Article
- White matter microstructure, traumatic brain injury, and disruptive behavior disorders in girls and boys.Frontiers in neuroscience · 2024Article
- Imaging of the superficial white matter in health and disease.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Premature white matter microstructure in female children with a history of concussion.Developmental cognitive neuroscience · 2023Article
- Short superficial white matter and aging: a longitudinal multi-site study of 1293 subjects and 2711 sessions.Aging brain · 2023Article
- Neuronal somatic plasmalemmal permeability and dendritic beading caused by head rotational traumatic brain injury in pigs-An exploratory study.Frontiers in cellular neuroscience · 2023Article
- Article
- Altered microstructural properties of superficial white matter in patients with Parkinson's disease.Brain imaging and behavior · 2022Article
- Neurons and glial cells acquire a senescent signature after repeated mild traumatic brain injury in a sex-dependent manner.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundDiffusion Tensor Imaging (DTI) studies of traumatic brain injury (TBI) have focused on alterations in microstructural features of deep white matter fibers (DWM), though post-mortem studies have demonstrated that injured axons are often observed at the gray-white matter interface where superficial white matter fibers (SWM) mediate local connectivity.
objectivesTo examine microstructural alterations in SWM and DWM in youths with a history of mild TBI and examine the relationship between white matter alterations and attention.
methodsUsing DTIDWM fractional anisotropy (FA) and SWM FA in youths with mild TBI (TBI, n=63) were compared to typically developing and psychopathology matched control groups (n=63 each). Following tract-based spatial statistics, SWM FA was assessed by applying a probabilistic tractography derived SWM mask, and DWM FA was captured with a white matter fiber tract mask. Voxel-wise z-score calculations were used to derive a count of voxels with abnormally high and low FA for each participant. Analyses examined DWM and SWM FA differences between TBI and control groups, the relationship between attention and DWM and SWM FA and the relative susceptibility of SWM compared to DWM FA to alterations associated with mild TBI.
resultsCase-based comparisons revealed more voxels with low FA and fewer voxels with high FA in SWM in youths with mild TBI compared to both control groups. Equivalent comparisons in DWM revealed a similar pattern of results, however, no group differences for low FA in DWM were found between mild TBI and the control group with matched psychopathology. Slower processing speed on the attention task was correlated with the number of voxels with low FA in SWM in youths with mild TBI.
conclusionsWithin a sample of youths with a history of mild TBI, this study identified abnormalities in SWM microstructure associated with processing speed. The majority of DTI studies of TBI have focused on long-range DWM fiber tracts, often overlooking the SWM fiber type.
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