Evidence map›Paper›PMID 31794716›Full record

ArticleDevelopmental cell2019

Prominin-2 Suppresses Ferroptosis Sensitivity.

Alexia Belavgeni, Stefan R Bornstein, Andreas Linkermann

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Therapeutic Implications of Ferroptosis in Renal Fibrosis.Frontiers in molecular biosciences · 2022
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Emerging mechanisms and targeted therapy of ferroptosis in cancer.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Review
  13. Article
  14. Article
  15. PLA2G6 guards placental trophoblasts against ferroptotic injury.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Alexia BelavgeniDivision of Nephrology, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Stefan R BornsteinDepartment of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Andreas LinkermannDivision of Nephrology, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany; Biotechnology Center, Technische Universität Dresden, 01307 Dresden, Germany. Electronic address: andreas.linkermann@ukdd.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis causes clinically relevant amounts of necrosis during the course of heart attacks and acute kidney injury. However, ferroptosis is still a very young research field. In this issue of Developmental Cell, Brown et al. describe the pentaspan membrane glycoprotein prominin-2 as a novel endogenous ferroptosis inhibitor.

Indexed as

FerroptosisIronAC133 AntigenHumansMembrane GlycoproteinsNecrosisAC133 AntigenIronMembrane Glycoproteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.