Evidence map›Paper›PMID 31794381›Full record

ArticleeLife2019

Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex.

Raphael M Bendriem, Shawn Singh, Alice Abdel Aleem, David A Antonetti, M Elizabeth Ross

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  4. Occludin acts as a dynein adaptor regulating permeability and collateral angiogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  11. Loss of symmetric cell division of apical neural progenitors drivesmedRxiv : the preprint server for health sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Raphael M BendriemCenter for Neurogenetics, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, United States.
Shawn SinghCenter for Neurogenetics, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, United States.
Alice Abdel AleemWeill Cornell Medicine Qatar, Doha, Qatar.
David A AntonettiKellogg Eye Center, Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, United States.
M Elizabeth RossCenter for Neurogenetics, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, United States.ORCID 0000-0001-6440-8089
Cornell University · USUniversity of Michigan · USWeill Cornell Medical College in Qatar · QA

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Risk Genes and Environment Interactions in NTDsP01HD067244 · NICHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI ROSS, MARGARET ELIZABETH · 2011 to 2020
$12.6M
Training Program in Developmental BiologyT32HD060600 · NICHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI BAO, ZHIRONG, STUHLMANN, HEIDI · 2010 to 2024
$3.5M
Progenitor Regulation Underlying Cortical Interneuron SpecificationR01NS105477 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI ROSS, MARGARET ELIZABETH · 2018 to 2022
$3.1M
NICHD NIH HHS P01 HD067244NICHD NIH HHS T32 HD060600NIDDK NIH HHS P30 DK020572NIH HHS P01HD067244NIH HHS R01NS105477NIH HHS Training Fellowship (T32HD060600)NINDS NIH HHS R01 NS105477
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AneuploidyAnimalsApoptosisCell DifferentiationCell ProliferationCentrosomeCerebral CortexCRISPR-Cas SystemsDisease Models, AnimalGene EditingHumansMiceMice, KnockoutMicrocephalyMicrotubulesMutagenesisOccludinbrain malformationcentrosome regulationcortical neurogenesishumanhuman biologymedicinemicrocephalymouseneuroscienceOCLNtight junction protein

Identifiers

PMID31794381
PMCPMC6890460
OpenAlexW2994071680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.