Evidence map›Paper›PMID 31794071›Full record

ReviewMedical physics2020

PET/MRI attenuation estimation in the lung: A review of past, present, and potential techniques.

Joseph Lillington, Ludovica Brusaferri, Kerstin Kläser, Karin Shmueli, Radhouene Neji, Brian F Hutton, Francesco Fraioli, Simon Arridge, Manuel Jorge Cardoso, Sebastien Ourselin and 2 more

Abstract readReview
In one paragraph

Review in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Synergistic motion compensation strategies for positron emission tomography when acquired simultaneously with magnetic resonance imaging.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021
    Review
  9. Review
  10. Attenuation correction for human PET/MRI studies.Physics in medicine and biology · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Joseph LillingtonCentre for Medical Imaging, University College London, London, W1W 7TS, UK.
Ludovica BrusaferriInstitute of Nuclear Medicine, University College London, London, NW1 2BU, UK.
Kerstin KläserCentre for Medical Image Computing, University College London, London, WC1E 7JE, UK.
Karin ShmueliMagnetic Resonance Imaging Group, Department of Medical Physics & Biomedical Engineering, University College London, London, WC1E 6BT, UK.
Radhouene NejiMR Research Collaborations, Siemens Healthcare Limited, Frimley, GU16 8QD, UK.
Brian F HuttonInstitute of Nuclear Medicine, University College London, London, NW1 2BU, UK.
Francesco FraioliInstitute of Nuclear Medicine, University College London, London, NW1 2BU, UK.
Simon ArridgeCentre for Medical Image Computing, University College London, London, WC1E 7JE, UK.
Manuel Jorge CardosoSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, SE1 7EH, UK.
Sebastien OurselinSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, SE1 7EH, UK.
Kris ThielemansInstitute of Nuclear Medicine, University College London, London, NW1 2BU, UK.
David AtkinsonCentre for Medical Imaging, University College London, London, W1W 7TS, UK.

Funding

National Institute for Health ResearchSiemens HealthineersUCL
6 · The paper itself

Abstract

Positron emission tomography/magnetic resonance imaging (PET/MRI) potentially offers several advantages over positron emission tomography/computed tomography (PET/CT), for example, no CT radiation dose and soft tissue images from MR acquired at the same time as the PET. However, obtaining accurate linear attenuation correction (LAC) factors for the lung remains difficult in PET/MRI. LACs depend on electron density and in the lung, these vary significantly both within an individual and from person to person. Current commercial practice is to use a single-valued population-based lung LAC, and better estimation is needed to improve quantification. Given the under-appreciation of lung attenuation estimation as an issue, the inaccuracy of PET quantification due to the use of single-valued lung LACs, the unique challenges of lung estimation, and the emerging status of PET/MRI scanners in lung disease, a review is timely. This paper highlights past and present methods, categorizing them into segmentation, atlas/mapping, and emission-based schemes. Potential strategies for future developments are also presented.

Indexed as

Magnetic Resonance ImagingPositron-Emission TomographyHumansImage Processing, Computer-AssistedLungRespirationattenuation estimationlungmagnetic resonance imagingmedical imagingpositron emission tomography

Identifiers

PMID31794071
PMCPMC7027532

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.