ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2020
The Association Between Smoking and Gut Microbiome in Bangladesh.
Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Intergenerational and individual effects of smoking exposure on non-alcoholic fatty liver disease: A Mendelian randomization study.Tobacco induced diseases · 2026Article
- The Bidirectional Interplay Between Substances of Abuse and Gut Microbiome Homeostasis.Life (Basel, Switzerland) · 2025Review
- Review
- Potential roles of cigarette smoking on gut microbiota profile among Chinese men.BMC medicine · 2025Article
- Gut Microbiota at the Crossroad of Hepatic Oxidative Stress and MASLD.Antioxidants (Basel, Switzerland) · 2025Review
- Maternal smoking around birth is associated with an increased risk of offspring constipation: Evidence from a Mendelian randomization study.Tobacco induced diseases · 2025Article
- Mouse model validity for studying the impact of tobacco smoke on the human gut microbiota assessed via in silico and experimental approaches.Tobacco induced diseases · 2025Article
- Understanding dysbiosis and resilience in the human gut microbiome: biomarkers, interventions, and challenges.Frontiers in microbiology · 2025Review
- Interplay of Oxidative Stress, Gut Microbiota, and Nicotine in Metabolic-Associated Steatotic Liver Disease (MASLD).Antioxidants (Basel, Switzerland) · 2024Review
- Altered interaction network in the gut microbiota of current cigarette smokers.Engineering microbiology · 2024Article
- Differential network connectivity analysis for microbiome data adjusted for clinical covariates using jackknife pseudo-values.BMC bioinformatics · 2024Article
- Effect of different forms of tobacco on the oral microbiome in healthy adults: a systematic review.Frontiers in oral health · 2024Review
- Impact of cigarette smoking on gut microbial dysbiosis: a structured literature review.Gut microbiome (Cambridge, England) · 2024Review
- Associations between Wastewater Microbiome and Population Smoking Rate Identified Using Wastewater-Based Epidemiology.Environment & health (Washington, D.C.) · 2023Article
- Cross-talks between gut microbiota and tobacco smoking: a two-sample Mendelian randomization study.BMC medicine · 2023Article
- Targeting Lung-Gut Axis for Regulating Pollution Particle-Mediated Inflammation and Metabolic Disorders.Cells · 2023Review
- Role of the gut-brain axis in HIV and drug abuse-mediated neuroinflammation.Advances in drug and alcohol research · 2023Review
- Human Microbiome Mixture Analysis Using Weighted Quantile Sum Regression.International journal of environmental research and public health · 2022Article
- Sex-Dependent Effects of Inhaled Nicotine on the Gut Microbiome.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Article
- Super-taxon in human microbiome are identified to be associated with colorectal cancer.BMC bioinformatics · 2022Article
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Authors and funding
17 authors.
Funding
Abstract
introductionEpidemiological studies that investigate alterations in the gut microbial composition associated with smoking are lacking. This study examined the composition of the gut microbiome in smokers compared with nonsmokers. AIMS AND
methodsStool samples were collected in a cross-sectional study of 249 participants selected from the Health Effects of Arsenic Longitudinal Study in Bangladesh. Microbial DNA was extracted from the fecal samples and sequenced by 16S rRNA gene sequencing. The associations of smoking status and intensity of smoking with the relative abundance or the absence and presence of individual bacterial taxon from phylum to genus levels were examined.
resultsThe relative abundance of bacterial taxa along the Erysipelotrichi-to-Catenibacterium lineage was significantly higher in current smokers compared to never-smokers. The odds ratio comparing the mean relative abundance in current smokers with that in never-smokers was 1.91 (95% confidence interval = 1.36-2.69) for the genus Catenibacterium and 1.89 (95% confidence interval = 1.39-2.56) for the family Erysipelotrichaceae, the order Erysipelotrichale, and the class Erysipelotrichi (false discovery rate-adjusted p values = .0008-.01). A dose-response association was observed for each of these bacterial taxa. The presence of Alphaproteobacteria was significantly greater comparing current with never-smokers (odds ratio = 4.85, false discovery rate-adjusted p values = .04).
conclusionsOur data in a Bangladeshi population are consistent with evidence of an association between smoking status and dosage with change in the gut bacterial composition. IMPLICATIONS: This study for the first time examined the relationship between smoking and the gut microbiome composition. The data suggest that smoking status may play an important role in the composition of the gut microbiome, especially among individuals with higher levels of tobacco exposure.
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