ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2020
Patient-reported pain, discomfort, and anxiety during magnetic resonance imaging-targeted prostate biopsy.
Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- PRE-POET: a qualitative interview-based study to explore patient-relevant factors in the context of prostate biopsy.BMC urology · 2025Article
- Impact of multiparametric MRI and prostate biopsies on anxiety and quality of life in men with suspected prostate cancer.BJUI compass · 2025Article
- Risk Factors and Contemporary Management Options for Pain and Discomfort Experienced During a Prostate Biopsy.Current urology reports · 2024Review
- Comparison of procedural anxiety and pain associated with conventional transrectal ultrasound prostate biopsy to magnetic resonance imaging-ultrasound fusion-guided biopsy: a prospective cohort trial.Prostate cancer and prostatic diseases · 2024Article
- Advanced prostate cancer diagnosed by bone metastasis biopsy immediately after initial negative prostate biopsy: a case report and literature review.Frontiers in oncology · 2024Article
- The Severity of Pain in Prostate Biopsy Depends on the Biopsy Sector.Journal of personalized medicine · 2023Article
- Prospective analysis of pain expectancy and experience during MR-fusion prostate biopsy: does reality match patients' expectancy?World journal of urology · 2022Article
- Pain control according to the periprostatic nerve block site in magnetic resonance imaging/transrectal targeted prostate biopsy.Scientific reports · 2022Article
- Efficacy of additional periprostatic apex nerve block on pain in each of 12 transrectal prostate core biopsies: a retrospective study.BMC urology · 2021Article
- Effect of Prolonged Duration of Transrectal Ultrasound-Guided Biopsy of the Prostate and Pre-Procedure Anxiety on Pain in Patients without Anesthesia.Research and reports in urology · 2021Article
- Editorial Comment: Comparison of pain levels in fusion prostate biopsy and standard TRUS-Guided biopsy.International braz j urol : official journal of the Brazilian Society of UrologyArticle
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
introductionThe addition of targeted prostate biopsy to systemic biopsy impacts patient experience. We examined patient-reported pain, discomfort, anxiety, and tolerability among men undergoing magnetic resonance imaging (MRI)-targeted prostate biopsy in addition to transrectal ultrasound-guided systematic biopsy compared to those undergoing systematic biopsy alone.
methodsAll patients underwent transrectal systematic 14-core biopsies. Patients with regions of interest on MRI underwent additional targeted biopsies. All patients received equivalent periprostatic nerve block. Four single-item, standard, 11-point numerical rating scales evaluating pain, discomfort, anxiety, and tolerability were completed immediately after biopsy. Differences in means were compared using t-tests. Correlation between rated domains was tested using Spearman's correlation coefficient.
resultsOf 273 consecutive patients, 195 (71%) underwent targeted biopsy and 188 (69%) had undergone prior biopsy. In all men, the median score for pain and tolerability was 3, while the median score for discomfort and anxiety was 4. Pain was rated at 7 or above by 15% of patients. Moderate correlation between pain, discomfort, anxiety, and tolerability of repeat biopsy was observed (Spearman's ρ between 0.48 and 0.76). Compared to patients undergoing systematic biopsy alone, men who received both targeted and systematic biopsies reported higher anxiety scores (difference 1.2; 95% confidence interval [CI] 0.4-2.0; p=0.004) and discomfort (difference 1.0; 95% CI 0.3-1.7; p<0.001).
conclusionsPatients undergoing targeted and systematic biopsies report more discomfort and anxiety than patients undergoing systematic biopsies alone. Absolute differences are small, and patients are willing to undergo repeat biopsy if advised. Interventions to reduce biopsy-related anxiety are needed.
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Registered trials
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