Evidence map›Paper›PMID 31793859›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2020

Incidentalomas of the prostate detected by 18-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography.

Miles P Mannas, Taeweon Lee, Maral Pourghiasian, Don C Wilson, Peter C Black

Abstract read
In one paragraph

Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Beyond the Primary Tumor: Malignancy Risk and Evaluation Strategies forMolecular imaging and radionuclide therapy · 2026
    Article
  3. Article
  4. Definitions of Incidental [Diagnostics (Basel, Switzerland) · 2024
    Review
  5. Review
  6. Diagnostics (Basel, Switzerland) · 2023
    Article
  7. Prevalence and Clinical Significance of Incidental FocalMolecular imaging and radionuclide therapy · 2022
    Article
  8. Beyond the Prognostic Value of 2-[Diagnostics (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Miles P MannasDepartment of Urologic Sciences, University of British Columbia, Vancouver BC, Canada; Vancouver Prostate Centre, Vancouver BC, Canada.
Taeweon LeeDepartment of Urologic Sciences, University of British Columbia, Vancouver BC, Canada; Vancouver Prostate Centre, Vancouver BC, Canada.
Maral PourghiasianDepartment of Urologic Sciences, University of British Columbia, Vancouver BC, Canada; Vancouver Prostate Centre, Vancouver BC, Canada.
Don C WilsonDepartment of Urologic Sciences, University of British Columbia, Vancouver BC, Canada; Vancouver Prostate Centre, Vancouver BC, Canada.
Peter C BlackDepartment of Urologic Sciences, University of British Columbia, Vancouver BC, Canada; Vancouver Prostate Centre, Vancouver BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionProstate incidentalomas are prostatic lesions suspicious for cancer discovered by imaging patients without a known history of prostatic cancer (PCa) for other reasons. 18-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG PET) is used to diagnose, stage, and assess response to treatment for numerous cancers, but it is not routinely used for PCa. We aimed to determine the rate of detection of prostate incidentalomas in patients undergoing FDG PET and to evaluate the natural history of these lesions.

methodsA retrospective review was conducted of all FDG PET scans performed between 2005 and 2017 at a single institution. Patients were selected who had prostatic uptake without a history of PCa. Clinical data were collected from electronic medical records to determine how the prostate incidentalomas were further evaluated and to define the rate of malignancy.

resultsA prostate incidentaloma was identified in 309 (1.0%) of 31 019 FDG PET scans performed on men. A prostate-specific antigen (PSA) test was obtained in 40.1% of patients within six months of prostate incidentaloma detection. Six patients underwent a multiparametric magnetic resonance imaging (mpMRI) of the prostate, which identified PCa in one case. Overall, PCa was diagnosed in 33 cases, representing 10.7% of the prostate incidentalomas and 0.1% of the scanned patients. PCa was intermediate- or high-risk in 27 (8.7%) of the prostate incidentalomas.

conclusionsIncidental lesions detected in the prostate by FDG PET may represent clinically significant PCa. Referral to a urologist for further evaluation should be considered if the patient is otherwise in reasonable health.

Identifiers

PMID31793859
PMCPMC7197962

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.