ArticleJournal of cancer survivorship : research and practice2020
Association between polypharmacy and health-related quality of life among cancer survivors in the United States.
Article in Journal of cancer survivorship : research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 22 citations in OpenAlex.
- Music Therapy Versus Cognitive Behavioral Therapy via Telehealth for Anxiety in Survivors of Cancer: A Randomized Clinical Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026Trial
- Prescription and Non-prescription Medication Pill Burdens and Their Associations with Health-Related Quality of Life in Older Adults: A Cross-Sectional Study.Drugs & aging · 2025Trial
- "This is my voice; this is my story": a thematic analysis of needs and challenges expressed in songs by adult cancer survivors.Journal of cancer survivorship : research and practice · 2026Article
- Polypharmacy among people diagnosed with colorectal cancer in Australia: a population-based cohort study.The oncologist · 2026Article
- Polypharmacy and quality of life in Yemeni cancer patients undergoing chemotherapy: A cross-sectional study.PLOS global public health · 2026Article
- Quality of life in older patients with cancer and related unmet needs: a scoping review.Acta oncologica (Stockholm, Sweden) · 2025Article
- Caregiving responsibility and psychological distress among community-dwelling cancer survivors in the United States.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Identifying central dimensions of quality of life including life-related values, preferences and functional health in older patients with cancer: a scoping review protocol.Frontiers in psychology · 2024Article
- Health-related quality of life and use of medication with anticholinergic activity in patients with multiple myeloma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Telehealth-Based Music Therapy Versus Cognitive Behavioral Therapy for Anxiety in Cancer Survivors: Rationale and Protocol for a Comparative Effectiveness Trial.JMIR research protocols · 2023Article
- The Use of Traditional, Complementary, and Integrative Medicine in Cancer: Data-Mining Study of 1 Million Web-Based Posts From Health Forums and Social Media Platforms.Journal of medical Internet research · 2023Article
- Battlefield acupuncture for chronic musculoskeletal pain in cancer survivors: a novel care delivery model for oncology acupuncture.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- The association between polypharmacy and health-related quality of life among non-dialysis chronic kidney disease patients.PloS one · 2023Article
- Factors associated with polypharmacy and the high risk of medication-related problems among older community-dwelling adults in European countries: a longitudinal study.BMC geriatrics · 2022Article
- The effect of polypharmacy on quality of life in adult patients with nonalcoholic fatty liver disease in the United States.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Observational
- Prognosis of C4 dislocation with spinal cord injury following psychological intervention.The Journal of international medical research · 2021Article
- Use of Chronic Prescription Medications and Prevalence of Polypharmacy in Survivors of Childhood Cancer.Frontiers in oncology · 2021Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePolypharmacy (PP) is present in many cancer survivors and may lead to lower health-related quality of life (HRQoL). The study's objective was to evaluate the association between PP and HRQoL among cancer survivors in the US.
methodsA cross-sectional analysis of the Medical Expenditure Panel Survey (MEPS) was conducted. Our analytic sample included all adult patients with cancer, during even years 2008-2014. PP was defined as reported use of five or more unique therapeutic classes of prescription medications. The MEPS measured HRQoL using the Short Form 12-Item Health Survey Version 2 (SF-12v2) physical component summary (PCS) and mental component summary (MCS) scores. Ordinary least squares regressions were used to assess associations between PP and HRQoL controlling for demographic, socioeconomic, and clinical factors.
resultsPP was prevalent among 44.4% of 10.1 million cancer survivors per calendar year (on average) for years 2008, 2010, 2012, and 2014. The mean adjusted PCS score for cancer survivors with PP was 35.8 points, which was significantly lower compared with cancer survivors without PP (39.5) by 3.7 points (p value < .0001). Conversely, the mean adjusted MCS scores were not significantly lower in cancer survivors with PP compared with cancer survivors without PP (44.9 versus 45.4, p value = 0.3145).
conclusionsPP was prevalent in 44.4% of cancer survivors and was associated with significantly poorer physical HRQoL than reported in their counterparts without PP. IMPLICATIONS FOR CANCER SURVIVORS: PP should be examined closely among cancer survivors because of increased association with poorer physical HRQoL.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.