ArticleInflammation2020
Immunostimulatory Activities of Coliphages on In Vitro Activated Mammalian Macrophages.
Article in Inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Molecular and biological characterization of a newly discovered Kayfunavirus bacteriophage targeting multidrug-resistant Escherichia coli from swine feces.Scientific reports · 2026Article
- Bacteriophages JEP7 and PBC2, which target foodborne pathogens, elicit cytokine responses in mammalian cells.Food science and biotechnology · 2026Article
- When bacteriophages encounter macrophages during their journey through the human body.Frontiers in cellular and infection microbiology · 2026Review
- Electrospun nanofiber mats caged the mammalian macrophages on their surfaces and prevented their inflammatory responses independent of the fiber diameter.Scientific reports · 2024Article
- Water-Based Synthesis of Copper Chalcogenide Structures and Their Photodynamic Immunomodulatory Activities on Mammalian Macrophages.Applied biochemistry and biotechnology · 2022Article
- Bacteriophage-based decontamination to control environmental colonization byFrontiers in cellular and infection microbiology · 2022Article
- Review
- Bacteriophages as an Alternative Method for Control of Zoonotic and Foodborne Pathogens.Viruses · 2021Review
- Interactions of Bacteriophages with Animal and Human Organisms-Safety Issues in the Light of Phage Therapy.International journal of molecular sciences · 2021Review
- Ruthenium Bipyridyl Dithiocyanate Complex Exerted Adjuvant Activity on the Activated Mammalian Macrophages in vitro.Inflammation · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteriophages present alternatives to antibiotics. In the age of superbugs and antibiotic resistance, the field of medicine is trying to create new antibiotics or derivatives of the old ones to eliminate bacterial infections. Bacteriophages are specific to a certain type of bacterial species and effectively kill the bacteria of target. In order to effectively use the bacteriophages as medicine, their possible side effects should be properly analyzed and one of those includes their activities on the immune system cells. In this study, we isolated two new Escherichia coli bacteriophages and tested their effect on the activation state of the mammalian macrophages. The bacteriophages were host specific and had substantial adsorption rates on E. coli. Moreover, they were able to effectively stimulate the macrophages in the absence of a bacterial stimulant, lipopolysaccharides. This implies that these bacteriophages can be used against E. coli infections in which proper immune system activation is missing. This study is the first one to our knowledge specifically showing the immunostimulatory effect of newly isolated E. coli bacteriophages on the macrophages. It is important to determine the effect of bacteriophages on the immune system cells before their use as antibiotics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.