Evidence map›Paper›PMID 31792691›Full record

ArticleSurgical endoscopy2020

Magnetic sphincter augmentation is an effective treatment for atypical symptoms caused by gastroesophageal reflux disease.

Marc A Ward, Ahmed Ebrahim, Jeffrey Kopita, Lindsay Arviso, Gerald O Ogola, Brittany Buckmaster, Steven G Leeds

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. [Treatment status and progress of laryngopharyngeal reflux disease].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Article
  5. Review article: Diagnosis and management of laryngopharyngeal reflux.Alimentary pharmacology & therapeutics · 2024
    Review
  6. Review
  7. How I Approach Laryngopharyngoesophageal Reflux (LPR).Current gastroenterology reports · 2021
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marc A WardCenter for Advanced Surgery, Baylor Scott and White Health, Dallas, TX, USA. Marc.Ward@bswhealth.org.ORCID 0000-0002-7147-3994
Ahmed EbrahimTexas A & M College of Medicine, Bryan, TX, USA.
Jeffrey KopitaPulmonary and Critical Care Specialists, Baylor Scott and White Health, Dallas, TX, USA.
Lindsay ArvisoDivision of Laryngology, Baylor University Medical Center, Dallas, TX, USA.
Gerald O OgolaCenter for Clinical Effectiveness, Baylor Scott and White Health, Dallas, TX, USA.
Brittany BuckmasterCenter for Advanced Surgery, Baylor Scott and White Health, Dallas, TX, USA.
Steven G LeedsCenter for Advanced Surgery, Baylor Scott and White Health, Dallas, TX, USA.
Baylor University Medical Center · USBaylor Scott & White Health · USBryan College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to determine whether magnetic sphincter augmentation (MSA) could effectively treat patients with gastroesophageal reflux disease (GERD) who suffer primarily from atypical symptoms due to laryngopharyngeal reflux (LPR). MSA has been shown to treat typical symptoms of GERD with good success, but its effect on atypical symptoms is unknown.

methodsA retrospective review of a prospectively maintained institutional review board-approved database was conducted for all patients who underwent MSA between January 2015 and December 2018. All patients had objective confirmation of GERD from ambulatory pH monitoring off anti-reflux medications (DeMeester score > 14.7). Symptoms were assessed preoperatively and at 1 year postoperatively using GERD Health-Related Quality of Life (GERD-HRQL) and Reflux Symptom Index (RSI) questionnaires.

resultsThere were 86 patients (38 males; 48 females) with a median age of 51.5 years. Total GERD HRQL scores improved from a mean of 38.79 to 6.53 (p < 0.01) and RSI scores improved from a mean of 20.9 to 8.1 (p < 0.01). Atypical symptoms evaluated from the RSI questionnaire include hoarseness, throat clearing, postnasal drip, breathing difficulties, and cough. All atypical symptoms were significantly improved at 1 year following MSA (p < 0.01). All three typical symptoms of heartburn, dysphagia, and regurgitation were significantly improved based on pre and postoperative GERD HRQL questionnaires (p < 0.02). Ninety-one percent of patients were off their PPI and dissatisfaction with their current therapy decreased from 95% preoperatively to 13% postoperatively.

conclusionMSA is an effective treatment for typical and atypical GERD symptoms.

Indexed as

LaparoscopyMagnetsAdultEsophageal Sphincter, LowerFemaleFollow-Up StudiesGastroesophageal RefluxHumansMaleMiddle AgedQuality of LifeRetrospective StudiesTreatment OutcomeAmbulatory pH testingAtypical symptomsGastroesophageal reflux disease (GERD)Laryngopharyngeal reflux disease (LPR)Magnetic sphincter augmentation

Identifiers

PMID31792691
OpenAlexW2989758002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.