Evidence map›Paper›PMID 31792575›Full record

SynthesisInternational orthopaedics2020

Diagnosis and treatment of mycoplasmal septic arthritis: a systematic review.

Y Chen, Z Huang, X Fang, W Li, B Yang, W Zhang

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International orthopaedics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. ExtragenitalIDCases · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Microbial culture vs. mNGS: diagnostic variations in periprosthetic joint infection.Frontiers in cellular and infection microbiology · 2025
    Article
  7. Periprosthetic joint infections: state-of-the-art.Archives of orthopaedic and trauma surgery · 2024
    Review
  8. A case report of fracture-related infection withJournal of bone and joint infection · 2024
    Article
  9. An Unusual and Difficult to Detect Cause of Infection in Two Trauma Patients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  10. Article
  11. Optimization and standardization of mNGS-based procedures for the diagnosis ofFrontiers in cellular and infection microbiology · 2023
    Article
  12. Article
  13. Septic arthritis caused byBMJ case reports · 2022
    Article
  14. Article
  15. Septic polyarthritis withAccess microbiology · 2021
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Y ChenDepartment of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350004, China.
Z HuangDepartment of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350004, China.
X FangDepartment of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350004, China.
W LiDepartment of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350004, China.
B YangDepartment of Laboratory Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350004, China.
W ZhangDepartment of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350004, China. zhangwm0591@fjmu.edu.cn.ORCID 0000-0003-1567-7279
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSeptic arthritis caused by Mycoplasma is rare. The diagnosis and effective treatment of mycoplasmal septic arthritis remains a serious problem for clinicians. The aim of this systematic review was to document the available evidence on the diagnosis and treatment methods for mycoplasmal septic arthritis and to provide guidance for clinicians.

methodsThe PubMed, EMBASE, and Cochrane Library databases were searched in December 2018.The searches were limited to the English language. Article screening and data extraction and compilation were conducted by two independent reviewers. All the included studies were assessed using the Methodological Index for Non-randomized Studies (MINORS) tool.

resultsThere was a total of 33 articles including 34 cases of mycoplasmal septic arthritis and eight of them were periprosthetic joint infection (PJI). Twenty-four patients (70.6%) were immunocompromised, and the synovial fluid white blood cell (WBC) count was significantly lower in the immunocompromised group than in the immunocompetent group (48,527 × 10

conclusionThe possibility of mycoplasmal septic arthritis should be considered if patients with joint infections have a history of immunocompromised, repeated negative cultures, and poor empiric antibiotic treatment results. The rational use of nucleic acid testing technologies can help in the clinical diagnosis and treatment of mycoplasmal septic arthritis.

Indexed as

Arthritis, InfectiousHumansMycoplasma InfectionsImmunocompromiseMycoplasmal septic arthritisNucleic acid testingPeriprosthetic joint infection

Identifiers

PMID31792575
OpenAlexW2993625043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.