ArticleScientific reports2019
Chest CTA in children younger than two years - a retrospective comparison of three contrast injection protocols.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Impact of contrast enhancement boost and super-resolution deep learning reconstruction on pediatric congenital heart disease CTA scans: ultra-low contrast dose.BMC medical imaging · 2025Article
- Weight-based flow rate triphasic contrast injection protocol for pediatric cardiac computed tomography.Quantitative imaging in medicine and surgery · 2025Article
- Thoracic CT Angiographies in Children Using Automated Power Injection with Bolus Tracking Versus Manual Contrast Injection: Analysis of Contrast Enhancement, Image Quality and Radiation Exposure.Diagnostics (Basel, Switzerland) · 2025Article
- Feasibility of U-Net model for cerebral arteries segmentation with low-dose computed tomography angiographic images with pre-processing methods.Scientific reports · 2025Article
- Role of photon-counting computed tomography in pediatric cardiovascular imaging.World journal of clinical pediatrics · 2025Review
- Correlation of patient characteristics with peak enhancement time for pediatric cardiac computed tomography in congenital heart disease.Journal of clinical imaging science · 2024Article
- The Correlation Between Body Mass Index and Computed Tomography Angiography on Vascular Positioning in Anterolateral Thigh Flap Transplantation.Journal of the Belgian Society of Radiology · 2022Article
- Cardiothoracic CTA in Infants Referred for Aortic Arch Evaluation-Retrospective Comparison of Iomeprol 350, Ioversol 350, Iopromide 370 and Iodixanol 320.Children (Basel, Switzerland) · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To obtain the highest diagnostic information with least side effects when performing thoracic CT angiography (CTA) is challenging in young children. The current study aims to compare three contrast agent (CA) injection protocols regarding image quality and CA characteristic: a standard CTA, a fixed-bolus delay protocol, and the "microbolus technique (MBT)" developed in our institution. Seventy chest CTA scans of patients (<2 years) were divided into three groups. MBT was applied in group I, the standard protocol in group II and a fixed bolus delay in group III. Objective image quality was assessed by measuring peak enhancement, image noise, signal-to-noise (SNR) and contrast-to-noise ratios (CNR). Two observers scored subjective image quality and artifacts. Significantly lower amounts of CA (mean ± SD) were used in the MBT group compared to Group II (9.0 ± 3.7 ml vs. 12.9 ± 4.5 ml). A lower, but still diagnostic (>400 HU) enhancement was registered in all major thoracic vessels in group I without significant differences regarding SNR and CNR in most regions (p < 0.05). The best scores for image quality and artifacts were reached in group I. All three chest CTA contrast injection protocols offered diagnostic vessel enhancement in young patients. MBT was associated with reduced image artifacts and less injected CA.
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