Trial reportScientific reports2019
Light therapy with boxes or glasses to counteract effects of acute sleep deprivation.
Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study of Effects of Light on the Vigilance and Cognitive Performance Following a Night Without Sleep
A Pilot Trial of Bright Light Therapy in Patients Receiving First Line Immune Checkpoint Blockade
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Dose-response effects of light therapy on sleepiness and circadian phase shift in shift workers: a meta-analysis and moderator analysis.Scientific reports · 2021Pooled it
- Exploratory crossover field study indicates efficacy and feasibility of light therapy glasses to mitigate fatigue in multiple sclerosis.Scientific reports · 2026Trial
- Nurse-delivered sleep restriction therapy to improve insomnia disorder in primary care: the HABIT RCT.Health technology assessment (Winchester, England) · 2024Trial
- Effects of light therapy on sleep and circadian rhythm in older type 2 diabetics living in long-term care facilities: a randomized controlled trial.Frontiers in endocrinology · 2024Trial
- Circadian acclimatization of performance, sleep, and 6-sulfatoxymelatonin using multiple phase shifting stimuli.Frontiers in endocrinology · 2022Trial
- Bright Light Therapy for Psychiatry Residents: A Pilot Study of Feasibility and Perceived Impact on Wellbeing.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026Article
- Therapeutic prospects of bright light therapy in addictive disorders: a scoping review.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Chronotherapy in the Treatment of Major Depression.Advances in experimental medicine and biology · 2026Review
- Pathophysiological Models of Hypersomnolence Associated With Depression.Biological psychiatry global open science · 2025Review
- Understanding the cognitive and neuroimaging bases underlying the detrimental impact of sleep deprivation on reciprocity.iScience · 2024Article
- Effects of light therapy on sleep/wakefulness, daily rhythms, and the central orexin system in a diurnal rodent model of seasonal affective disorder.Journal of affective disorders · 2023Article
- Article
- Review
- The Effectiveness of Blue-Light-Emitting Glasses in Security Guards Exposed to Night Shift Work on Work-Related and General Fatigue: A Randomised Controlled Cross-Over Study.Clocks & sleep · 2022Article
- Effects of Lighting Interventions to Improve Sleepiness in Night-Shift Workers: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2022Review
- The melanopsin-mediated pupil response is reduced in idiopathic hypersomnia with long sleep time.Scientific reports · 2022Article
- A Growing Link between Circadian Rhythms, Type 2 Diabetes Mellitus and Alzheimer's Disease.International journal of molecular sciences · 2022Review
- Possible Effects of Bright Light Therapy on Electroencephalogram-Vigilance in the Treatment of Depression in Adolescents: A Pilot Study.Frontiers in psychiatry · 2022Article
- Validity and Usage of the Seasonal Pattern Assessment Questionnaire (SPAQ) in a French Population of Patients with Depression, Bipolar Disorders and Controls.Journal of clinical medicine · 2021Article
- Beneficial effects of daytime high-intensity light exposure on daily rhythms, metabolic state and affect.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep deprivation, in the context of shift work, is an increasing major public health issue. We aimed to determine whether early light administration can counteract sleep deprivation effects, and to compare LED-glasses with a traditional light therapy box. This cross-over design study included 18 individuals exposed to light therapy for 30 minutes at 5 am after one night of complete sleep deprivation, to mimic the night shift condition. Individuals were randomly exposed to 10,000 Lux light box, 2,000 Lux LED blue-enriched glasses, and control (ambient dim-light at 8 lux). Alertness, cognition and mood were assessed throughout the night and following morning. Five women and 13 men (mean 24.78 year old) presented with a progressive and increasing alteration of alertness, cognition, and mood during each sleep deprivation. A rebound was observed at 8 am resulting from the circadian drive overriding cumulative sleep homeostatic effects. Morning light significantly improved sleepiness and sustained attention from 5 to 7 am. These effects were comparable between devices and significantly different from control. Both devices were overall well and similarly tolerated. Early morning light therapy in the condition of sleep loss may have broad practical applications to improve sleepiness, sustained attention and subsequent risk of accidents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.