Evidence map›Paper›PMID 31791962›Full record

Trial reportBMJ open2019

Paramedic attitudes and experiences of enrolling patients into the PARAMEDIC-2 adrenaline trial: a qualitative survey within the London Ambulance Service.

Johanna Lazarus, Rajeshwari Iyer, Rachael T Fothergill

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Evaluating the current breadth of randomized control trials on cardiac arrest: A scoping review.Journal of the American College of Emergency Physicians open · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Johanna LazarusLondon Ambulance Service NHS Trust, London, UK.
Rajeshwari IyerLondon Ambulance Service NHS Trust, London, UK.
Rachael T FothergillLondon Ambulance Service NHS Trust, London, UK rachael.fothergill@lond-amb.nhs.uk.ORCID 0000-0003-1341-6200
London Ambulance Service NHS Trust · GBUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to gather the views and experiences of paramedics who participated in a large-scale randomised controlled drug trial and to identify barriers to recruitment.

designWe surveyed paramedics using a questionnaire consisting of a mix of closed and open ended questions.

settingThe study was conducted within the London Ambulance Service, London, UK.

participants150 paramedics who were trained to enrol patients into the PARAMEDIC-2 randomised controlled trial of adrenaline versus placebo in out-of-hospital cardiac arrest and who returned the questionnaire.

results98% of study participants felt prehospital research was very important, and 97.3% reported an overall positive experience of being involved in a drug trial. Only 5.3% felt uncomfortable enrolling patients into the trial without prior consent from the patient or a relative. Over one- third (39.3%) identified one or more barriers to patient recruitment, the most common being the attitudes of other staff.

conclusionWe found a strong appetite for involvement in prehospital research among paramedics and an understanding of the importance of research that prevailed over the complexities of the trial. This is an important finding demonstrating that potentially ethically controversial research can be undertaken successfully by paramedics in the prehospital environment.

Indexed as

Attitude of Health PersonnelEmergency Medical TechniciansPatient SelectionQualitative ResearchEmergency Medical ServicesEpinephrineHumansIncidenceLondonOut-of-Hospital Cardiac ArrestSurveys and QuestionnairesSurvival RateSympathomimeticsTreatment OutcomeEpinephrineSympathomimeticsconsent in researchEMS researchparamedic attitudespre-hospital research

Identifiers

PMID31791962
PMCPMC6924800
OpenAlexW2990548139

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.