Evidence map›Paper›PMID 31791951›Full record

ArticleApplied and environmental microbiology2020

Electronic Cigarette (E-Cigarette) Vapor Exposure Alters the Streptococcus pneumoniae Transcriptome in a Nicotine-Dependent Manner without Affecting Pneumococcal Virulence.

Kamal Bagale, Santosh Paudel, Hayden Cagle, Erin Sigel, Ritwij Kulkarni

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05213936 (Scalp Cooling for Chemotherapy-Induced Alopecia in Patients of Color), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05213936 narecruitingnot on this mapstarted 2022, after this paper: background citation

Scalp Cooling for Chemotherapy-Induced Alopecia in Patients of Color: A Clinical and Mechanistic Study

TypeinterventionalSponsorMontefiore Medical CenterRan2022 to 2027Enrolled41ConditionsAlopeciaArmsScalp cooling with hairstyle, Scalp cooling with conditioner and water emulsion
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Transcriptomic analysis ofMicrobial genomics · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Effect of Cigarette and E-Cigarette Smoke Condensates onInternational journal of environmental research and public health · 2022
    Article
  12. Vaping and Lung Inflammation and Injury.Annual review of physiology · 2022
    Review
  13. The chemistry and toxicology of vaping.Pharmacology & therapeutics · 2021
    Review
  14. Electronic Cigarettes and Oral Health.Journal of dental research · 2021
    Article
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kamal BagaleDepartment of Biology, University of Louisiana at Lafayette, Lafayette, Louisiana, USA.
Santosh PaudelDepartment of Biology, University of Louisiana at Lafayette, Lafayette, Louisiana, USA.
Hayden CagleDepartment of Biology, University of Louisiana at Lafayette, Lafayette, Louisiana, USA.
Erin SigelDepartment of Biology, University of Louisiana at Lafayette, Lafayette, Louisiana, USA.
Ritwij KulkarniDepartment of Biology, University of Louisiana at Lafayette, Lafayette, Louisiana, USA ritwij.kulkarni@louisiana.edu.
University of Louisiana at Lafayette · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of electronic cigarette (e-cigarette) vapor (EV) exposure on the physiology of respiratory microflora are not fully defined. We analyzed the effects of exposure to vapor from nicotine-containing and nicotine-free e-liquid formulations on the virulence and transcriptome of

Indexed as

TranscriptomeAnimalsE-Cigarette VaporElectronic Nicotine Delivery SystemsMiceMice, Inbred C57BLNicotinePneumonia, PneumococcalStreptococcus pneumoniaeVirulenceE-Cigarette VaporNicotineacute pneumoniabiofilmse-cigaretteRNA-SeqStreptococcus pneumoniaetranscriptomevaping

Identifiers

PMID31791951
PMCPMC6974656
OpenAlexW2991470812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.