Evidence map›Paper›PMID 31791946›Full record

ArticleAntimicrobial agents and chemotherapy2020

New Triazole NT-a9 Has Potent Antifungal Efficacy against Cryptococcus neoformans

Ren-Yi Lu, Ting-Jun-Hong Ni, Jing Wu, Lan Yan, Quan-Zhen Lv, Li-Ping Li, Da-Zhi Zhang, Yuan-Ying Jiang

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Antimicrobial agents and chemotherapy · 2025
    Article
  3. Current research in microbial sciences · 2025
    Article
  4. Discovery of novel thiosemicarbazone derivatives with potent and selective anti-Journal of enzyme inhibition and medicinal chemistry · 2023
    Article
  5. Article
  6. ExploringJournal of fungi (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ren-Yi Lu *School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.ORCID 0000-0001-6539-8089
Ting-Jun-Hong Ni *Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Jing Wu *School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Lan YanSchool of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Quan-Zhen LvSchool of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Li-Ping LiShanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Da-Zhi ZhangSchool of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China zdzhang_yjhx@smmu.edu.cn 13761571578@163.com.
Yuan-Ying JiangShanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China zdzhang_yjhx@smmu.edu.cn 13761571578@163.com.
Second Military Medical University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past decades, the incidence of cryptococcosis has increased dramatically, which poses a new threat to human health. However, only a few drugs are available for the treatment of cryptococcosis. Here, we described a leading compound, NT-a9, an analogue of isavuconazole, that showed strong antifungal activities

Indexed as

AnimalsAntifungal AgentsCryptococcosisCryptococcus neoformansFemaleHumansMiceMice, Inbred ICRTriazolesAntifungal AgentsTriazolesCryptococcus neoformansdisseminated cryptococcosisfungal burdenNT-a9triazole compound

Identifiers

PMID31791946
PMCPMC6985734
OpenAlexW2991497900

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.